{"doi":"10.7554/elife.57968","title":"Functional links between sensory representations, choice activity, and sensorimotor associations in parietal cortex","abstract":"Three-dimensional (3D) representations of the environment are often critical for selecting actions that achieve desired goals. The success of these goal-directed actions relies on 3D sensorimotor transformations that are experience-dependent. Here we investigated the relationships between the robustness of 3D visual representations, choice-related activity, and motor-related activity in parietal cortex. Macaque monkeys performed an eight-alternative 3D orientation discrimination task and a visually guided saccade task while we recorded from the caudal intraparietal area using laminar probes. We found that neurons with more robust 3D visual representations preferentially carried choice-related activity. Following the onset of choice-related activity, the robustness of the 3D representations further increased for those neurons. We additionally found that 3D orientation and saccade direction preferences aligned, particularly for neurons with choice-related activity, reflecting an experience-dependent sensorimotor association. These findings reveal previously unrecognized links between the fidelity of ecologically relevant object representations, choice-related activity, and motor-related activity.","journal":"eLife","year":2020,"id":83713,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":11,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9517,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":430407,"name":"Raymond Doudlah","orcid":"0000-0003-3631-5947","position":1,"is_corresponding":false},{"id":430408,"name":"Byoung‐Hoon Kim","orcid":"0000-0001-7159-5134","position":2,"is_corresponding":false},{"id":430409,"name":"Adhira Sunkara","orcid":"0000-0001-8605-9879","position":3,"is_corresponding":false},{"id":399858,"name":"Lowell Thompson","orcid":"0000-0002-8453-7002","position":4,"is_corresponding":false},{"id":431351,"name":"Meghan E Lowe","orcid":null,"position":5,"is_corresponding":false},{"id":399859,"name":"Ari Rosenberg","orcid":"0000-0002-8606-2987","position":6,"is_corresponding":false},{"id":430406,"name":"Ting‐Yu Chang","orcid":"0000-0003-3964-0905","position":0,"is_corresponding":true}],"reference_count":74,"raw_metadata":null,"created_at":"2026-07-18T21:54:32.422022Z","pmid":"33078705","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}