{"doi":"10.7326/annals-24-03353","title":"Diet and Risk for Incident Diverticulitis in Women","abstract":"BACKGROUND: Patients with diverticulitis often attempt to control their diet with a particular focus on avoiding nuts and seeds. However, whether dietary patterns or dietary intake of nuts and seeds are associated with diverticulitis risk is poorly studied, particularly in women. OBJECTIVE: To determine whether select diets affect incident diverticulitis risk in women. DESIGN: Prospective cohort study. SETTING: Cohort study in the United States and Puerto Rico. PARTICIPANTS: = 29 916). INTERVENTION: Food frequency questionnaires were used to calculate dietary index scores and to assess intake of nuts, seeds, and corn. MEASUREMENTS: Cox proportional hazards regression was used to estimate adjusted hazard ratios (aHRs) and 95% CIs for the associations between each dietary component or dietary index and diverticulitis risk. RESULTS: 1531 cases of incident diverticulitis for 415 103 person-years of follow-up were identified. Intake of peanuts, nuts, and seeds (aHR,1.07 [95% CI, 0.91 to 1.25]) and fresh fruits with edible seeds (aHR,1.06 [CI, 0.90 to 1.24]) was not associated with incident diverticulitis. There was a reduced risk for incident diverticulitis in women in the highest quartile of healthy diets compared with the lowest quartile: the Dietary Approaches to Stop Hypertension diet (aHR, 0.77 [CI, 0.65 to 0.90]), the Healthy Eating Index (aHR, 0.78 [CI, 0.66 to 0.91]), the Alternative Healthy Eating Index (aHR, 0.81 [CI, 0.69 to 0.95]), and the Alternative Mediterranean diet (aHR, 0.91 [CI, 0.78 to 1.06]). LIMITATION: Confounding, selection bias, and measurement bias are possible. CONCLUSION: Healthy diets were associated with a reduced risk for incident diverticulitis in women. Consumption of nuts and seeds was not associated with diverticulitis risk. PRIMARY FUNDING SOURCE: National Institutes of Health.","journal":"Annals of Internal Medicine","year":2025,"id":521109,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9625,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":349844,"name":"Chelsea Anderson","orcid":"0000-0001-6535-481X","position":1,"is_corresponding":false},{"id":275144,"name":"Hazel B. Nichols","orcid":"0000-0003-0972-1560","position":2,"is_corresponding":false},{"id":770113,"name":"Anna C. Salvador","orcid":"0000-0003-4218-631X","position":3,"is_corresponding":false},{"id":280896,"name":"Robert S. Sandler","orcid":"0000-0002-1323-6245","position":4,"is_corresponding":false},{"id":104612,"name":"Dale P. Sandler","orcid":"0000-0002-6776-0018","position":5,"is_corresponding":false},{"id":218575,"name":"Anne F. Peery","orcid":"0000-0002-2005-0780","position":6,"is_corresponding":false},{"id":1122588,"name":"Trevor Barlowe","orcid":"0009-0002-1507-3539","position":0,"is_corresponding":true}],"reference_count":37,"raw_metadata":null,"created_at":"2026-07-19T02:49:32.958846Z","pmid":"40324196","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}