{"doi":"10.7150/ijms.39432","title":"Provoking factors for postpartum chronic hypertension in women with preceding gestational hypertension/preeclampsia: A longitudinal cohort study of 22,798 pregnancies","abstract":null,"journal":"International Journal of Medical Sciences","year":2020,"id":663030,"datarank":0.41588830833596724,"base_score":2.772588722239781,"endowment":2.772588722239781,"self_citation_contribution":0.41588830833596724,"citation_network_contribution":0.0,"self_endowment_contribution":0.41588830833596724,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":15,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":2,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1730994,"name":"Li-Ru Chen","orcid":null,"position":1,"is_corresponding":false},{"id":1730993,"name":"Kuo-Hu Chen","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Provoking factors for postpartum chronic hypertension in women with preceding gestational hypertension/preeclampsia: A longitudinal cohort study of 22,798 pregnancies","abstract":"Background: A proportion of women with pregnancies complicated by gestational hypertension/preeclampsia (GH-PE) will have persistent postpartum chronic hypertension (CHTN). Common risk factors for postpartum CHTN include older age, pre-existing CHTN, smoking, pre-pregnancy obesity (elevated BMI), and co-morbidities such as thyroid disorders. However, most of explored risk factors are pre-pregnancy factors, and were mainly based on studies with small sample size. Methods: To investigate provoking pre-pregnancy and intra-pregnancy factors for postpartum CHTN in women with preceding GH-PE, the cohort study enrolled 22,798 index pregnancies to analyze individual characteristics, co-morbidities and postpartum outcomes after excluding women with pre-existing CHTN. Results: Among 2,132 GH-PE pregnancies, 428 (20.1%) were complicated with postpartum CHTN. After adjustment, logistic regression analysis revealed excessive pregnant weight gain (10 kgw at 28 weeks' gestation) (OR: 14.50, 95% CI: 11.02-19.08) and gestational diabetes mellitus (GDM) (OR: 6.25, 95% CI: 4.98-7.85) were major risk factors for developing CHTN, other than age (OR: 1.80, 95% CI: 1.68-1.93), pre-pregnancy BMI (OR: 3.15, 95% CI: 2.75-3.60), severity of GH-PE (OR: 2.46, 95% CI: 1.97-3.07), smoking (OR: 1.79, 95% CI: 1.35-2.38), and overt DM (OR: 2.30, 95% CI: 1.73-3.06). Conclusion: Excessive pregnant weight gain and GDM are major intra-pregnancy risk factors for postpartum CHTN in women with preceding GH-PE. Future studies should investigate interventions such as a healthy diet, appropriate physical exercise and avoidance of excessive pregnant weight gain as a means to reduce the frequency of CHTN following pregnancy.","is_dataset_classified":null,"base_score":2.772588722239781,"endowment":2.772588722239781,"datacite_reuse_total":2,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"32174785","pmcid":"PMC7053303","openalex_id":"https://openalex.org/W3005535400","authors":[],"funders":[],"total_grants":0,"fwci":0.736,"citation_percentile":0.76346255,"influential_citations":0,"citation_trend":[{"year":2021,"count":1},{"year":2022,"count":7},{"year":2024,"count":3},{"year":2025,"count":3},{"year":2026,"count":1}],"oa_status":"gold","license":"cc-by-nc","oa_locations":[{"url":"https://www.medsci.org/v17p0543.pdf","host_type":"journal"},{"url":"https://www.medsci.org/v17p0543.pdf","host_type":"publisher"},{"url":"http://www.medsci.org/v17p0543.htm","host_type":"publisher"},{"url":"https://doi.org/10.7150/ijms.39432","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/32174785","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7053303","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC7053303","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC7053303?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Pregnancy and preeclampsia studies","Birth, Development, and Health"],"mesh_terms":["Adult","Female","Humans","Hypertension","Longitudinal Studies","Obesity","Pre-Eclampsia","Pregnancy","Pregnancy Complications, Cardiovascular","Regression Analysis","Risk Factors","Smoking","Thyroid Diseases","Weight Gain","Body Mass Index","Diabetes, Gestational","Hypertension, Pregnancy-Induced","Postpartum Period"],"keywords":["Medicine","Obstetrics","Pregnancy","Gestational diabetes","Gestational hypertension","Preeclampsia","Body mass index","Cohort study","Cohort","Gestation","Weight gain","Gynecology","Internal medicine","Body weight","Gestational Diabetes Mellitus","Chronic Hypertension","Pregnant Weight Gain"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[{"doi":"10.6084/m9.figshare.21019177.v1","title":"Additional file 1 of Screening high-risk population of persistent postpartum hypertension in women with preeclampsia using latent class cluster analysis","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.21019177","title":"Additional file 1 of Screening high-risk population of persistent postpartum hypertension in women with preeclampsia using latent class cluster analysis","publisher":"figshare","resource_type":"JournalArticle"}],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"doi"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-12T19:10:33.848006Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}