{"doi":"10.5588/pha.20.0020","title":"Choice architecture-based prescribing tool for TB preventive therapy: a pilot study in South Africa","abstract":"BACKGROUND: All people with HIV who screen negative for active tuberculosis (TB) should receive isoniazid preventive therapy (IPT). IPT implementation remains substantially below the 90% WHO target. This study sought to further understanding of IPT prescription by piloting a simplified prescribing approach. SETTING: Primary care clinics in Matlosana, South Africa. DESIGN: This was a mixed-methods implementation study. METHODS: Nine providers were recruited and underwent training on 2018 WHO guidelines. A simplified prescribing tool containing antiretroviral therapy (ART) and IPT prescriptions was introduced into the workflow for 2 weeks. Prescription data were collected from file review. Interviews were conducted with prescribers. RESULTS: During the study period, 41 patients were evaluated for ART initiation; 34 (83%) files used the simplified prescribing tool. Thirty-seven (90%) patients were eligible for same-day ART and IPT initiation, of whom 36 (97%) received IPT prescription. Qualitative interviews identified the following barriers to IPT prescription: cognitive burden, extensive documentation, limited management support, paucity of training, stock-outs, and patient-related factors. Provider acceptability of the tool was favorable, with unanimous recommendation to colleagues on the basis of streamlining documentation and reminding to prescribe. CONCLUSIONS: This simplified prescribing device for IPT was feasible to implement. Streamlining documentation and reminding providers to prescribe can reduce work-flow barriers to IPT provision.","journal":"Public Health Action","year":2020,"id":110154,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9519,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":483440,"name":"Joshua Materi","orcid":"0000-0001-9786-9068","position":1,"is_corresponding":false},{"id":525897,"name":"Anthony P. Lombardo","orcid":null,"position":2,"is_corresponding":false},{"id":524961,"name":"Minja Milovanovic","orcid":"0000-0002-4654-8755","position":3,"is_corresponding":false},{"id":525898,"name":"Nompumelelo Yende","orcid":null,"position":4,"is_corresponding":false},{"id":524962,"name":"Ebrahim Variava","orcid":"0000-0003-2888-789X","position":5,"is_corresponding":false},{"id":378803,"name":"Jonathan E. Golub","orcid":"0000-0003-2398-3145","position":6,"is_corresponding":false},{"id":231934,"name":"Neil Martinson","orcid":"0000-0002-0184-5705","position":7,"is_corresponding":false},{"id":418029,"name":"Christopher J. Hoffmann","orcid":"0000-0002-9422-0519","position":8,"is_corresponding":false},{"id":524960,"name":"Giorgio Caturegli","orcid":"0000-0001-6508-7096","position":0,"is_corresponding":true}],"reference_count":23,"raw_metadata":null,"created_at":"2026-07-18T23:12:57.988348Z","pmid":"33134126","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}