{"doi":"10.5551/jat.64096","title":"Association of Anthropometric and CT-Based Obesity Indices with Subclinical Atherosclerosis","abstract":"AIM: Few studies have compared the strength in the associations of anthropometric and computed tomography (CT)-based obesity indices with coronary artery calcification (CAC), aortic artery calcification (AoAC), and aortic valve calcification (AVC). METHODS: We assessed cross-sectcional associations of anthropometric and CT-based obesity indices with CAC, AoAC, and AVC. Anthropometric measures included body mass index (BMI), waist circumference, hip ircumference, waist-to-hip circumference ratio, and waist-to-height ratio in 931 men (mean age, 63.7 years) from a population-based cohort. CT images at the L4/5 level were obtained to calculate the areas of abdominal visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), total adipose tissue (TAT), VAT-to-SAT ratio (VSR), and VAT-to-TAT ratio (VTR). CAC, AoAC, and AVC were quantified using the Agatston score based on CT scanning. RESULTS: CAC, AVC, and AoAC were present in 348 (62.6%), 173 (18.6%), and 769 (82.6%) participants, respectively. In multivariable models adjusting for age, lifestyle factors, and CT types (electron beam CT and multidetector row CT), anthropometric and CT-based obesity indices were positively associated with CAC (p＜0.01). Conversely, VAT-to-SAT ratio and VAT-to-TAT ratio were positively associated with AoAC (p＜0.01). Any obesity indices were not associated with AVC. CONCLUSIONS: The strength of the associations of obesity indices with subclinical atherosclerosis varied according to the anatomically distinct atherosclerotic lesions, among men.","journal":"Journal of Atherosclerosis and Thrombosis","year":2023,"id":352877,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.96,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":373795,"name":"Takashi Hisamatsu","orcid":"0000-0002-6244-1763","position":1,"is_corresponding":false},{"id":930920,"name":"Yoshihisa Nakagawa","orcid":"0000-0002-9411-9314","position":2,"is_corresponding":false},{"id":930918,"name":"Yuichi Sawayama","orcid":"0000-0002-9409-0056","position":3,"is_corresponding":false},{"id":1005203,"name":"Yuichiro Yano","orcid":"0000-0001-6425-1747","position":4,"is_corresponding":false},{"id":318508,"name":"Aya Kadota","orcid":"0000-0001-7378-0544","position":5,"is_corresponding":false},{"id":373794,"name":"Akira Fujiyoshi","orcid":"0000-0002-5790-7119","position":6,"is_corresponding":false},{"id":1005204,"name":"Sayaka Kadowaki","orcid":"0000-0002-2419-5274","position":7,"is_corresponding":false},{"id":930919,"name":"Sayuki Torii","orcid":"0000-0002-3104-9208","position":8,"is_corresponding":false},{"id":373796,"name":"Keiko Kondo","orcid":"0000-0002-9709-4474","position":9,"is_corresponding":false},{"id":1005205,"name":"Yoshiyuki Watanabe","orcid":"0000-0003-3906-3730","position":10,"is_corresponding":false},{"id":37772,"name":"Hirotsugu Ueshima","orcid":"0000-0002-7742-4253","position":11,"is_corresponding":false},{"id":37771,"name":"Katsuyuki Miura","orcid":"0000-0002-2646-9582","position":12,"is_corresponding":false},{"id":1005202,"name":"Yosuke Higo","orcid":"0000-0003-0660-1336","position":0,"is_corresponding":true}],"reference_count":51,"raw_metadata":null,"created_at":"2026-07-19T01:12:54.209378Z","pmid":"37558497","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}