{"doi":"10.5530/pj.2021.13.184","title":"Effect of Muntingia calabura L. Leaf Extract on Blood Glucose Levels and Body Weight of Alloxan-Induced Diabetic Mice","abstract":null,"journal":"Pharmacognosy Journal","year":2021,"id":670764,"datarank":0.5101796072493234,"base_score":3.4011973816621555,"endowment":3.4011973816621555,"self_citation_contribution":0.5101796072493234,"citation_network_contribution":0.0,"self_endowment_contribution":0.5101796072493234,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":29,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1752217,"name":"Gahastanira Permata Solikhah","orcid":null,"position":1,"is_corresponding":false},{"id":1752216,"name":"Tridiganita Intan Solikhah","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Effect of Muntingia calabura L. Leaf Extract on Blood Glucose Levels and Body Weight of Alloxan-Induced Diabetic Mice","abstract":"Objective: To evaluate the effect of Muntingia calabura L. leaf extract on the blood glucose level and weight of alloxan-induced diabetic mice. Methods: The mice were injected using 150mg/kg of alloxan intraperitoneally to induce diabetes. Blood glucose level was tested before alloxan injection and 5 days after injection to confirm diabetes development. M. calabura leaf extract with 100 and 300 mg/kg and 600 g/kg of glibenclamide was given orally for 14 days. Results: The statistical results showed a significant decrease in blood glucose level, especially on day-7 and day-14 in the M. calabura leaf extract treatment group and glibenclamide treatment group compared to the model control group. There was an increase of weight on day-7 and day-14 in the M. calabura leaf extract group and a significant decrease in weight on day-7 in the glibenclamide group compared to the model control group. Conclusion: M. calabura leaf extract had a significant antidiabetic effect that can normalize the weight of alloxan-induced diabetic mice.","is_dataset_classified":null,"base_score":3.4011973816621555,"endowment":3.4011973816621555,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19162232","pmcid":null,"openalex_id":"https://openalex.org/W3213680367","authors":[],"funders":[],"total_grants":0,"fwci":4.5095,"citation_percentile":0.94114012,"influential_citations":0,"citation_trend":[{"year":2021,"count":1},{"year":2022,"count":7},{"year":2023,"count":8},{"year":2024,"count":6},{"year":2025,"count":5},{"year":2026,"count":2}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://www.phcogj.com/sites/default/files/PharmacognJ-13-6-1450_0.pdf","host_type":"journal"},{"url":"https://www.phcogj.com/sites/default/files/PharmacognJ-13-6-1450_0.pdf","host_type":"publisher"},{"url":"https://doi.org/10.5530/pj.2021.13.184","host_type":"journal"}],"fields_of_study":["Medicinal Plant Research","thermodynamics and calorimetric analyses","Moringa oleifera research and applications"],"mesh_terms":[],"keywords":["Glibenclamide","Alloxan","Diabetes mellitus","Traditional medicine","Body weight","Positive control","Medicine","Internal medicine","Endocrinology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-15T23:42:52.290257Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}