{"doi":"10.5334/tohm.300","title":"Clinical Outcome and Characterization of Local Field Potentials in Holmes\n                        Tremor Treated with Pallidal Deep Brain Stimulation","abstract":null,"journal":"Tremor and Other Hyperkinetic Movements","year":2016,"id":641784,"datarank":0.29188652235829704,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.0,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1668877,"name":"Brian C. Kaszuba","orcid":null,"position":1,"is_corresponding":false},{"id":1668878,"name":"Lucy Gee","orcid":null,"position":2,"is_corresponding":false},{"id":1668879,"name":"Julia Prusik","orcid":null,"position":3,"is_corresponding":false},{"id":1668880,"name":"Fabio Danisi","orcid":null,"position":4,"is_corresponding":false},{"id":1668881,"name":"Damian Shin","orcid":null,"position":5,"is_corresponding":false},{"id":677551,"name":"Julie G Pilitsis","orcid":null,"position":6,"is_corresponding":false},{"id":1668876,"name":"Adolfo Ramirez-Zamora","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Clinical Outcome and Characterization of Local Field Potentials in Holmes\n                        Tremor Treated with Pallidal Deep Brain Stimulation","abstract":"<strong>Background:</strong> Holmes tremor (HT) is an irregular, low-frequency rest tremor associated with prominent action and postural tremors. Currently, the most effective stereotactic target and neurophysiologic characterization of HT, specifically local field potentials (LFPs) are uncertain. We present the outcome, intraoperative neurophysiologic analysis with characterization of LFPs in a patient managed with left globus pallidus interna deep brain stimulation (Gpi DBS). <strong>Case Report:</strong> A 24-year-old male underwent left Gpi DBS for medically refractory HT. LFPs demonstrated highest powers in the delta range in Gpi. At the 6-month follow-up, a 90% reduction in tremor was observed. <strong>Discussion:</strong> Pallidal DBS should be considered as an alternative target for management of refractory HT. LFP demonstrated neuronal activity associated with higher power in the delta region, similarly seen in patients with generalized dystonia.","is_dataset_classified":null,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19767382","pmcid":null,"openalex_id":"https://openalex.org/W4250102971","authors":[],"funders":[{"funder_name":"National Institutes of Health","grant_id":"5R01CA166379-08","title":"MR-Guided Precision Conformal Ablation Therapy for Brain Tumors"}],"total_grants":1,"fwci":0.4218,"citation_percentile":0.69724091,"influential_citations":0,"citation_trend":[{"year":2017,"count":1},{"year":2019,"count":1},{"year":2021,"count":1},{"year":2022,"count":1},{"year":2023,"count":2}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://doi.org/10.5334/tohm.300","host_type":"journal"},{"url":"https://doi.org/10.5334/tohm.300","host_type":"publisher"},{"url":"http://www.tremorjournal.org/articles/10.5334/tohm.300/galley/441/download/","host_type":""},{"url":"https://dx.doi.org/10.7916/d8rj4jt8","host_type":""},{"url":"https://pubmed.ncbi.nlm.nih.gov/27441097","host_type":""},{"url":"http://dx.doi.org/10.7916/D8S182JJ","host_type":""},{"url":"https://doaj.org/article/ec185634822043dfb2409a8f2b1cc157","host_type":""},{"url":"https://doi.org/https://doi.org/10.7916/D8RJ4JT8","host_type":""}],"fields_of_study":["Neurological disorders and treatments","Genetic Neurodegenerative Diseases","Photoreceptor and optogenetics research","03 medical and health sciences","0302 clinical medicine"],"mesh_terms":[],"keywords":["Deep brain stimulation","Local field potential","Dystonia","Globus pallidus","Refractory (planetary science)","Stimulation","Essential tremor","Neuroscience","Refractory period","Medicine","Subthalamic nucleus","Psychology","Basal ganglia","Physical medicine and rehabilitation","Anesthesia","Parkinson's disease","Internal medicine","Physics","Disease","Central nervous system","FOS: Clinical medicine","Neurosciences","610","Neurophysiology","Diseases of the musculoskeletal system","Case Reports","576","RC925-935","Brain stimulation","Tremor","Neurology. Diseases of the nervous system","RC346-429"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-07T20:19:18.817651Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}