{"doi":"10.5281/zenodo.17726137","title":"Code for \"Human and bacterial genetic variation shape oral microbiomes and health\"","abstract":"Code for \"Human and bacterial genetic variation shape oral microbiomes and health\", 1) extraction of unmapped reads in SPARK and quantification of microbial relative abundances with MetaPhlAn 4, 2) Copy number estimation for AMY1 and PRB1, 3) PSV genotyping in AMY1, 4) extraction of unmapped reads in SPARK and alignment to microbial references, 5) normalization of read depth. Summary statistics from genome-wide association study for oral microbiome composition. These were generated by testing each genetic variant for association with each microbial-abundance PC, after which we summed the 439 test statistics obtained per variant to compute a single, combined association test for each variant. As individual test statistics were merged without considering effect direction to identify loci with pleiotropic effects, these are unsigned.","journal":"Zenodo (CERN European Organization for Nuclear Research)","year":2025,"id":586165,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":0.0,"corpus_rank":10062,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.9304,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1500603,"name":"Handsaker, Robert E.","orcid":null,"position":1,"is_corresponding":false},{"id":38264,"name":"Margaux L. A. Hujoel","orcid":"0000-0001-9116-1712","position":2,"is_corresponding":false},{"id":38265,"name":"Ronen E. Mukamel","orcid":"0000-0002-9042-9673","position":3,"is_corresponding":false},{"id":1500604,"name":"Usher, Christina L.","orcid":null,"position":4,"is_corresponding":false},{"id":1158,"name":"Steven A. McCarroll","orcid":"0000-0002-6954-8184","position":5,"is_corresponding":false},{"id":24619,"name":"Po‐Ru Loh","orcid":"0000-0001-5542-9064","position":6,"is_corresponding":false},{"id":16695,"name":"Nolan Kamitaki","orcid":"0000-0003-0614-0189","position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-19T02:59:28.666390Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}