{"doi":"10.5281/zenodo.17538303","title":"Workshop Report: Functional evidence evaluation workshop, June 2024","abstract":"This document reports the findings from the online workshop entitled “Functional Evidence Evaluation” held 19 June 2024 as part of the AusMAVE Education Project. The workshop discussed the central recommendations and guidelines on functional evidence use (Richards et al., 2015 and Brnich et al., 2019) along with recommendations on evaluating MAVE functional assays (Gelman et al., 2019). The workshop presented some examples across a range of functional assays. This report has been generated from the results of the workshop consultation, available at https://doi.org/10.5281/zenodo.17461665. The workshop was developed in response to the discussion and activities from participants in the “Functional Evidence and how to use it” workshop in November 2023, 10.5281/zenodo.13129941, to build on information previously presented on the incorporation of functional evidence into variant classification. The workshop also provided variant case-based activities that will be translated to an accessible resource and shared at a later date. The workshop was an activity of the AusMAVEEducation Project. The AusMAVE Education Project aims to support increased use of functional data/evidence, especially with the increasing body of high throughput functional data. It is an Australian research project funded by the Medical Research Future Fund, APP2015946. These polls were undertaken with oversight from the Human Research Ethics Committee of QIMR Berghofer, Project ID P3920. The workshop was co-designed, informed by representatives of identified stakeholders in the AusMAVE Education Project and represents part of a developing project supporting functional evidence use.","journal":"Zenodo (CERN European Organization for Nuclear Research)","year":2024,"id":508639,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7891,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":55382,"name":"Amanda B. Spurdle","orcid":"0000-0003-1337-7897","position":1,"is_corresponding":false},{"id":561883,"name":"Alan F. Rubin","orcid":"0000-0003-1474-605X","position":2,"is_corresponding":false},{"id":1197386,"name":"Rehan M. Villani","orcid":"0000-0001-8857-6271","position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T02:11:10.049781Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}