{"doi":"10.5204/thesis.eprints.246091","title":"Molecular recognition of anion binding proteins: Characterization and inhibition","abstract":"Anionic molecules play essential roles in our biology, controlled by a complex system of proteins that when something goes wrong, critical health problems can arise. This thesis combined computational tools and laboratory-based assays to investigate how some of these proteins recognize molecules and attempt to find small molecules that could help address these health problems. The three publications each study a different protein – LexA, which helps bacteria develop antibiotic resistance; human single-stranded binding protein 1, implicated in cancer; and the SARS-CoV-2 spike protein, studying how it infects cells.","journal":"Queensland University of Technology","year":2023,"id":415570,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9613,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1135901,"name":"Zachariah P. Schuurs","orcid":"0000-0002-5598-5252","position":0,"is_corresponding":true}],"reference_count":426,"raw_metadata":null,"created_at":"2026-07-19T01:22:12.933438Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}