{"doi":"10.51982/bagimli.1706693","title":"Factors influencing smoking cessation success in an outpatient clinic: a cross-sectional study","abstract":"<jats:p>Objective: Smoking remains a major global health issue, contributing to millions of preventable deaths annually. Effective smoking cessation strategies combine pharmacotherapy and behavioral support, yet real-world data on factors influencing treatment success in outpatient settings, particularly in Türkiye, are limited. The aim of this study was to evaluate the effectiveness of pharmacological treatment in a smoking cessation outpatient clinic and identify factors associated with cessation success.Method: This cross-sectional observational study included 203 adult smokers initiating pharmacological treatment at a tertiary hospital in Istanbul between April and October 2023. After excluding 22 patients lost to follow-up, 181 participants were analyzed. Data were collected via face-to-face interviews, the Fagerström Test for Nicotine Dependence (FTND), and 3-month follow-up calls. Bivariate analyses and multivariate logistic regression identified predictors of cessation success.Results: At 3-month follow-up, 28.6% of participants successfully quit smoking. Significant predictors of cessation included follow-up attendance (OR=0.18, p&lt;0.001), lower nicotine dependence (OR=1.33, p=0.011), combination therapy (bupropion + nicotine replacement therapy; p=0.001), and employment status (OR=0.39, p=0.036). Age, gender, education, and income were not significantly associated with outcomes.Conclusion: Pharmacotherapy, particularly combination therapy, combined with follow-up visits and tailored to nicotine dependence levels, enhances smoking cessation success. Sustained behavioral support and adherence-focused strategies are critical for optimizing outcomes in clinical practice.</jats:p>","journal":"Journal of Dependence","year":2025,"id":633348,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1641998,"name":"Furkan Alp Eren","orcid":null,"position":1,"is_corresponding":false},{"id":1641999,"name":"Hacer Hicran Mutlu","orcid":null,"position":2,"is_corresponding":false},{"id":1641997,"name":"Hasan Özcan Demir","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Factors influencing smoking cessation success in an outpatient clinic: a cross-sectional study","abstract":"<jats:p>Objective: Smoking remains a major global health issue, contributing to millions of preventable deaths annually. Effective smoking cessation strategies combine pharmacotherapy and behavioral support, yet real-world data on factors influencing treatment success in outpatient settings, particularly in Türkiye, are limited. The aim of this study was to evaluate the effectiveness of pharmacological treatment in a smoking cessation outpatient clinic and identify factors associated with cessation success.Method: This cross-sectional observational study included 203 adult smokers initiating pharmacological treatment at a tertiary hospital in Istanbul between April and October 2023. After excluding 22 patients lost to follow-up, 181 participants were analyzed. Data were collected via face-to-face interviews, the Fagerström Test for Nicotine Dependence (FTND), and 3-month follow-up calls. Bivariate analyses and multivariate logistic regression identified predictors of cessation success.Results: At 3-month follow-up, 28.6% of participants successfully quit smoking. Significant predictors of cessation included follow-up attendance (OR=0.18, p&lt;0.001), lower nicotine dependence (OR=1.33, p=0.011), combination therapy (bupropion + nicotine replacement therapy; p=0.001), and employment status (OR=0.39, p=0.036). Age, gender, education, and income were not significantly associated with outcomes.Conclusion: Pharmacotherapy, particularly combination therapy, combined with follow-up visits and tailored to nicotine dependence levels, enhances smoking cessation success. Sustained behavioral support and adherence-focused strategies are critical for optimizing outcomes in clinical practice.</jats:p>","is_dataset_classified":null,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19910364","pmcid":null,"openalex_id":"https://openalex.org/W4412792352","authors":[],"funders":[],"total_grants":0,"fwci":0.7367,"citation_percentile":0.7278019,"influential_citations":0,"citation_trend":[{"year":2026,"count":1}],"oa_status":"bronze","license":"https://creativecommons.org/licenses/by-nc-nd/4.0","oa_locations":[{"url":"https://dergipark.org.tr/en/download/article-file/4903486","host_type":"journal"},{"url":"https://dergipark.org.tr/en/download/article-file/4903486","host_type":"publisher"},{"url":"http://jod.akademisyen.net/index.php/jod/article/download/604/618","host_type":"publisher"},{"url":"https://doi.org/10.51982/bagimli.1706693","host_type":"journal"}],"fields_of_study":["Smoking Behavior and Cessation","Respiratory and Cough-Related Research","School Health and Nursing Education"],"mesh_terms":[],"keywords":["Cross-sectional study","Smoking cessation","Medicine","Outpatient clinic","Family medicine","Environmental health","Internal medicine"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-06T11:54:26.724152Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}