{"doi":"10.48550/arxiv.2512.20344","title":"A DeepSeek-Powered AI System for Automated Chest Radiograph Interpretation in Clinical Practice","abstract":"A global shortage of radiologists has been exacerbated by the significant volume of chest X-ray workloads, particularly in primary care. Although multimodal large language models show promise, existing evaluations predominantly rely on automated metrics or retrospective analyses, lacking rigorous prospective clinical validation. Janus-Pro-CXR (1B), a chest X-ray interpretation system based on DeepSeek Janus-Pro model, was developed and rigorously validated through a multicenter prospective trial (NCT07117266). Our system outperforms state-of-the-art X-ray report generation models in automated report generation, surpassing even larger-scale models including ChatGPT 4o (200B parameters), while demonstrating reliable detection of six clinically critical radiographic findings. Retrospective evaluation confirms significantly higher report accuracy than Janus-Pro and ChatGPT 4o. In prospective clinical deployment, AI assistance significantly improved report quality scores, reduced interpretation time by 18.3% (P < 0.001), and was preferred by a majority of experts in 54.3% of cases. Through lightweight architecture and domain-specific optimization, Janus-Pro-CXR improves diagnostic reliability and workflow efficiency, particularly in resource-constrained settings. The model architecture and implementation framework will be open-sourced to facilitate the clinical translation of AI-assisted radiology solutions.","journal":"arXiv (Cornell University)","year":2025,"id":4247,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.048,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-12-23","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":42722,"name":"Ruiheng Zhang","orcid":null,"position":1,"is_corresponding":false},{"id":42723,"name":"Yu Lei","orcid":null,"position":2,"is_corresponding":false},{"id":42724,"name":"Xuhua Duan","orcid":null,"position":3,"is_corresponding":false},{"id":42725,"name":"Jingfeng Yao","orcid":null,"position":4,"is_corresponding":false},{"id":42726,"name":"Shuguang Ju","orcid":null,"position":5,"is_corresponding":false},{"id":42727,"name":"Chaoyang Wang","orcid":null,"position":6,"is_corresponding":false},{"id":42728,"name":"Wei Yao","orcid":null,"position":7,"is_corresponding":false},{"id":42729,"name":"Yiwan Guo","orcid":null,"position":8,"is_corresponding":false},{"id":42730,"name":"Guilin Zhang","orcid":"0009-0003-8889-2559","position":9,"is_corresponding":false},{"id":42731,"name":"Chao Wan","orcid":"0000-0001-8643-6662","position":10,"is_corresponding":false},{"id":42732,"name":"Yuan Qian","orcid":"0000-0001-6361-8033","position":11,"is_corresponding":false},{"id":29056,"name":"Lei Chen","orcid":"0000-0002-5733-5026","position":12,"is_corresponding":false},{"id":42733,"name":"Wenjuan Tang","orcid":null,"position":13,"is_corresponding":false},{"id":42734,"name":"Biqiang Zhu","orcid":"0000-0002-4950-554X","position":14,"is_corresponding":false},{"id":42735,"name":"Xinggang Wang","orcid":null,"position":15,"is_corresponding":false},{"id":42736,"name":"Tao Sun","orcid":null,"position":16,"is_corresponding":false},{"id":351,"name":"Wei Zhou","orcid":"0000-0001-7534-3065","position":17,"is_corresponding":false},{"id":42737,"name":"Dacheng Tao","orcid":null,"position":18,"is_corresponding":false},{"id":42738,"name":"Yongchao Xu","orcid":null,"position":19,"is_corresponding":false},{"id":42739,"name":"Chuansheng Zheng","orcid":"0000-0002-2435-1417","position":20,"is_corresponding":false},{"id":42740,"name":"Huangxuan Zhao","orcid":null,"position":21,"is_corresponding":false},{"id":42741,"name":"Bo Du","orcid":"0000-0001-9306-6962","position":22,"is_corresponding":false},{"id":42721,"name":"Yaowei Bai","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":null,"created_at":"2026-03-01T18:20:47.508186Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}