{"doi":"10.48539/hbm556.jjrr.824","title":"Anatomical Structures, Cell Types, plus Biomarkers (ASCT+B) table for Small Intestine, v1.3","abstract":"Anatomical Structures, Cell Types, plus Biomarkers (ASCT+B) tables (https://humanatlas.io/asctb-tables) aim to capture<br>anatomical human body parts, the typology of cells, and biomarkers used to identify cell types. The tables are<br>authored and reviewed by an international team of experts. The Small Intestine ASCT+B table represents terms related<br>to the adult human small intestine. These include both macroscopic and microscopic anatomical structures, major cell<br>types, and protein biomarkers specific for each cell type listed. This table was generated based on published<br>histopathologic nomenclature, as well as published literature on cell-type specific biomarkers. Most of the markers<br>listed are observed in more than one study or orthogonally validated. Note that these are predicted markers and a<br>single marker to annotate a cell type is not likely sufficient or specific. Where more refined cell types are not<br>available in the ontologies, the closest general term is used. For example, there are likely multiple types of small<br>intestine stromal cells; however, further characterization is needed to distinguish between these cell types. Where<br>cells of similar type occur in different locations, the closest and highest level of resolution available is used. For<br>example, enterocytes occur in multiple different contexts within the small intestine, including the duodenum, jejunum,<br>and ileum.<br> <br>**Bibliography:** <br><br>* Börner, Katy, Sarah A. Teichmann, Ellen M. Quardokus, James C. Gee, Kristen Browne, David Osumi-Sutherland, Bruce W. Herr II, et al. 2021. “Anatomical Structures, Cell Types and Biomarkers of the Human Reference Atlas.” *Nature Cell Biology* 23 (11): 1117–28. https://doi.org/10.1038/s41556-021-00788-6.","journal":"The Human BioMolecular Atlas Program (HuBMAP) Reference Repository","year":2025,"id":586428,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":0.0,"corpus_rank":10062,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.9432,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":311539,"name":"Teri A. Longacre","orcid":"0000-0002-0935-7300","position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-19T02:59:28.666390Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}