{"doi":"10.4314/ijbcs.v3i3.45341","title":"Protective effects of pineapple (Ananas comosus) on liver and kidney of Wistar rats intoxicated with Doliprane®","abstract":null,"journal":"International Journal of Biological and Chemical Sciences","year":2009,"id":679426,"datarank":0.29188652235829704,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.0,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1775177,"name":"TM Kpodekon","orcid":null,"position":1,"is_corresponding":false},{"id":1775178,"name":"A Laleye","orcid":null,"position":2,"is_corresponding":false},{"id":1775176,"name":"TJ Dougnon","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Protective effects of pineapple (Ananas comosus) on liver and kidney of Wistar rats intoxicated with Doliprane®","abstract":"Effect of pineapple (Ananas comosus) on liver and kidney detoxication was studied in Wistar rats. Rats were treated with paracetamol at the dose of 2 g/kg of body weight per day for 6 weeks and then by Ananas comosus’ extract (0.06 - 0.12 ml/kg body weight). Administration of paracetamol induced hepatomegaly with a centrolobular necrosis and an increase in kidney weight. Treatment with Ananas comosus’ extract induced a reduction of hepatic lesions but no effect on kidney. These data suggest that Ananas comosus extract treatment reduces hepatotoxicity of paracetamol in Wistar rats.Keywords: Ananas comosus, Wistar rats, paracetamol, liver, kidney, detoxication.","is_dataset_classified":null,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21097893","pmcid":null,"openalex_id":"https://openalex.org/W1976771039","authors":[],"funders":[],"total_grants":0,"fwci":0.391,"citation_percentile":0.73372979,"influential_citations":0,"citation_trend":[{"year":2014,"count":1},{"year":2016,"count":1},{"year":2020,"count":1},{"year":2021,"count":1},{"year":2023,"count":1}],"oa_status":"gold","license":"cc-by-nc-sa","oa_locations":[{"url":"https://www.ajol.info/index.php/ijbcs/article/download/45341/28823","host_type":"journal"},{"url":"https://www.ajol.info/index.php/ijbcs/article/download/45341/28823","host_type":"publisher"},{"url":"https://doi.org/10.4314/ijbcs.v3i3.45341","host_type":"journal"}],"fields_of_study":["Drug-Induced Hepatotoxicity and Protection","Garlic and Onion Studies","Nigella sativa pharmacological applications"],"mesh_terms":[],"keywords":["Ananas","Kidney","Body weight","Detoxication","Chemistry","Pharmacology","Endocrinology","Medicine","Biology","Botany","Biochemistry","Enzyme"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-17T13:08:30.944146Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}