{"doi":"10.4269/ajtmh.2005.73.1050","title":"ARAGUARI VIRUS, A NEW MEMBER OF THE FAMILY ORTHOMYXOVIRIDAE: SEROLOGIC, ULTRASTRUCTURAL, AND MOLECULAR CHARACTERIZATION","abstract":"This paper reports the results of serologic, structural, biochemical, and genetic studies indicating that Araguari virus, a previously unassigned viral agent, is a member of the family Orthomyxoviridae and genus Thogotovirus. Araguari virus has six RNA fragments; biologically, it shares several properties with other viruses in the family Orthomyxoviridae. Nucleotide sequencing of the RNA segments 4 (glycoprotein) and 5 (nucleoprotein) of Araguari virus aligned with the orthomyxoviruses, showing the closest relationship with Thogoto virus (sequence similarity = 61.9% and 69.1%, respectively, for glycoprotein and nucleoprotein), but also sharing a more distant similarity with Dhori and Influenza C viruses, especially for the glycoprotein gene. Based on these results, we propose that Araguari virus should be assigned as a new member of the family Orthomyxoviridae and genus Thogotovirus.","journal":"The American Journal of Tropical Medicine and Hygiene","year":2005,"id":680232,"datarank":0.515098080672772,"base_score":3.4339872044851463,"endowment":3.4339872044851463,"self_citation_contribution":0.515098080672772,"citation_network_contribution":0.0,"self_endowment_contribution":0.515098080672772,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":30,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1777290,"name":"AMELIA P. A. TRAVASSOS DA ROSA","orcid":null,"position":1,"is_corresponding":false},{"id":1777293,"name":"MÁRCIO R. T. NUNES","orcid":null,"position":2,"is_corresponding":false},{"id":1777295,"name":"JOSÉ A. P. DINIZ","orcid":null,"position":3,"is_corresponding":false},{"id":1777297,"name":"ROBERT B. TESH","orcid":null,"position":4,"is_corresponding":false},{"id":1777298,"name":"ANA C. R. CRUZ","orcid":null,"position":5,"is_corresponding":false},{"id":1777300,"name":"CONCEIÇÃO M. A. VIEIRA","orcid":null,"position":6,"is_corresponding":false},{"id":1777301,"name":"PEDRO F. C. VASCONCELOS","orcid":null,"position":7,"is_corresponding":false},{"id":1777287,"name":"ELIANA V. PINTO DA SILVA","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"ARAGUARI VIRUS, A NEW MEMBER OF THE FAMILY ORTHOMYXOVIRIDAE: SEROLOGIC, ULTRASTRUCTURAL, AND MOLECULAR CHARACTERIZATION","abstract":"This paper reports the results of serologic, structural, biochemical, and genetic studies indicating that Araguari virus, a previously unassigned viral agent, is a member of the family Orthomyxoviridae and genus Thogotovirus. Araguari virus has six RNA fragments; biologically, it shares several properties with other viruses in the family Orthomyxoviridae. Nucleotide sequencing of the RNA segments 4 (glycoprotein) and 5 (nucleoprotein) of Araguari virus aligned with the orthomyxoviruses, showing the closest relationship with Thogoto virus (sequence similarity = 61.9% and 69.1%, respectively, for glycoprotein and nucleoprotein), but also sharing a more distant similarity with Dhori and Influenza C viruses, especially for the glycoprotein gene. Based on these results, we propose that Araguari virus should be assigned as a new member of the family Orthomyxoviridae and genus Thogotovirus.","is_dataset_classified":null,"base_score":3.4339872044851463,"endowment":3.4339872044851463,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"16354811","pmcid":null,"openalex_id":"https://openalex.org/W2128848100","authors":[],"funders":[{"funder_name":"NIAID NIH HHS","grant_id":"N01-AI30027","title":null}],"total_grants":1,"fwci":0.9862,"citation_percentile":0.8006227,"influential_citations":0,"citation_trend":[{"year":2014,"count":3},{"year":2015,"count":1},{"year":2016,"count":1},{"year":2017,"count":1},{"year":2018,"count":3},{"year":2019,"count":2},{"year":2020,"count":1},{"year":2021,"count":2},{"year":2022,"count":3},{"year":2023,"count":2},{"year":2024,"count":1},{"year":2025,"count":2}],"oa_status":"bronze","license":null,"oa_locations":[{"url":"http://www.ajtmh.org/deliver/fulltext/14761645/73/6/0731050.pdf?itemId=%2Fcontent%2Fjournals%2F10.4269%2Fajtmh.2005.73.1050&mimeType=pdf&containerItemId=content/journals/14761645","host_type":"journal"},{"url":"http://www.ajtmh.org/deliver/fulltext/14761645/73/6/0731050.pdf?itemId=%2Fcontent%2Fjournals%2F10.4269%2Fajtmh.2005.73.1050&mimeType=pdf&containerItemId=content/journals/14761645","host_type":"publisher"},{"url":"https://doi.org/10.4269/ajtmh.2005.73.1050","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/16354811","host_type":"repository"},{"url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.526.2747","host_type":""}],"fields_of_study":["Mosquito-borne diseases and control","Vibrio bacteria research studies","Viral Infections and Vectors"],"mesh_terms":["Animals","Base Sequence","Chlorocebus aethiops","Complement Fixation Tests","Hemagglutination Inhibition Tests","Marsupialia","Microscopy, Electron, Scanning","Molecular Sequence Data","Orthomyxoviridae","RNA, Viral","Vero Cells","Microscopy, Immunoelectron","Sequence Alignment","DNA, Complementary","Microscopy, Electron, Transmission"],"keywords":["Nucleoprotein","Orthomyxoviridae","Virology","Virus","Biology","Influenza A virus","Influenzavirus B","Nucleic acid sequence","Glycoprotein","Gene","Genetics"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-17T14:40:27.025384Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}