{"doi":"10.4172/2379-1764.1000196","title":"Sandwich ELISA for Circulating Myeloperoxidase- and Neutrophil Elastase-DNA Complexes Released from Neutrophil Extracellular Traps","abstract":null,"journal":"Advanced Techniques in Biology & Medicine","year":2017,"id":622279,"datarank":0.586803450814222,"base_score":3.912023005428146,"endowment":3.912023005428146,"self_citation_contribution":0.586803450814222,"citation_network_contribution":0.0,"self_endowment_contribution":0.586803450814222,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":49,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":16,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1607725,"name":"Muhammad Aminul Huq","orcid":null,"position":1,"is_corresponding":false},{"id":1607726,"name":"Masanobu Tsuda","orcid":null,"position":2,"is_corresponding":false},{"id":1607727,"name":"Hiroshi Noguchi","orcid":null,"position":3,"is_corresponding":false},{"id":1607728,"name":"Naoshi Takeyama","orcid":null,"position":4,"is_corresponding":false},{"id":1607724,"name":"Hideki Kano","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Sandwich ELISA for Circulating Myeloperoxidase- and Neutrophil Elastase-DNA Complexes Released from Neutrophil Extracellular Traps","abstract":"Neutrophil extracellular traps (NETs) are DNA scaffolds released by activated neutrophils that contain enzymes from neutrophil granules, such as myeloperoxidase (MPO), neutrophil elastase (NE) and cathepsin-G. NETs are produced by neutrophils in response to various stimuli, including invasion of pathogenic microorganisms. Here we describe a new ELISA method for quantifying the circulating levels of MPO- and NE-associated DNA in human plasma.","is_dataset_classified":null,"base_score":3.912023005428146,"endowment":3.912023005428146,"datacite_reuse_total":16,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19910364","pmcid":null,"openalex_id":"https://openalex.org/W2594636043","authors":[],"funders":[],"total_grants":0,"fwci":0.7725,"citation_percentile":0.6886957,"influential_citations":0,"citation_trend":[{"year":2018,"count":1},{"year":2019,"count":5},{"year":2020,"count":1},{"year":2021,"count":4},{"year":2022,"count":3},{"year":2023,"count":9},{"year":2024,"count":21},{"year":2025,"count":3},{"year":2026,"count":2}],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://doi.org/10.4172/2379-1764.1000196","host_type":"journal"}],"fields_of_study":["Neutrophil, Myeloperoxidase and Oxidative Mechanisms","Immune cells in cancer","Nitric Oxide and Endothelin Effects"],"mesh_terms":[],"keywords":["Neutrophil extracellular traps","Myeloperoxidase","Neutrophil elastase","Elastase","Neutrophile","Chemistry","Immunology","DNA","Extracellular","Microbiology","Biology","Biochemistry","Inflammation","Enzyme"],"sdg_mappings":[],"linked_datasets":[{"doi":"10.6084/m9.figshare.26669661.v1","title":"Additional file 1 of What is the actual relationship between neutrophil extracellular traps and COVID-19 severity? 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