{"doi":"10.4168/aard.2023.11.4.211","title":"Whole lung lavage with granulocyte macrophage colony-stimulating factor inhalation in children with pulmonary alveolar proteinosis: A case report","abstract":null,"journal":"Allergy, Asthma & Respiratory Disease","year":2023,"id":634417,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1645410,"name":"Min Jee Park","orcid":null,"position":1,"is_corresponding":false},{"id":1645411,"name":"Kun Baek Song","orcid":null,"position":2,"is_corresponding":false},{"id":1645412,"name":"Eom Ji Choi","orcid":null,"position":3,"is_corresponding":false},{"id":1645413,"name":"Eun Young Paek","orcid":null,"position":4,"is_corresponding":false},{"id":1645416,"name":"Dakyeong Lee","orcid":null,"position":5,"is_corresponding":false},{"id":1409371,"name":"Soo‐Jong Hong","orcid":"0000-0003-1409-2113","position":6,"is_corresponding":false},{"id":1645408,"name":"Siyoon Kim","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Whole lung lavage with granulocyte macrophage colony-stimulating factor inhalation in children with pulmonary alveolar proteinosis: A case report","abstract":"Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by hypoxemic respiratory failure due to the accumulation of lipoproteinaceous material in alveolar macrophages and alveoli.It has been reported that granulocyte macrophage colony-stimulating factor (GM-CSF) inhalation or whole lung lavage significantly improves the disease state.We present a case of 17-year-old female diagnosed with PAP and treated with both GM-CSF inhalation and whole lung lavage.Her symptoms, imaging findings, and pulmonary function tests improved after these treatments.Therefore, combined treatments of whole lung lavage and subsequent GM-CSF inhalation should be considered a treatment option for children and adolescents.(","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19767382","pmcid":null,"openalex_id":"https://openalex.org/W4388015606","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.23894164,"influential_citations":0,"citation_trend":[],"oa_status":"gold","license":"cc-by-nc","oa_locations":[{"url":"http://aard.or.kr/Synapse/Data/PDFData/9993AARD/aard-11-211.pdf","host_type":"journal"},{"url":"http://aard.or.kr/Synapse/Data/PDFData/9993AARD/aard-11-211.pdf","host_type":"publisher"},{"url":"https://aard.or.kr/pdf/10.4168/aard.2023.11.4.211","host_type":"publisher"},{"url":"https://aard.or.kr/DOIx.php?id=10.4168/aard.2023.11.4.211","host_type":"publisher"},{"url":"https://doi.org/10.4168/aard.2023.11.4.211","host_type":"journal"}],"fields_of_study":["Neonatal Respiratory Health Research","Congenital Diaphragmatic Hernia Studies","Respiratory Support and Mechanisms"],"mesh_terms":[],"keywords":["Pulmonary alveolar proteinosis","Inhalation","Alveolar macrophage","Granulocyte macrophage colony-stimulating factor","Medicine","Granulocyte","Lung","Pathology","Macrophage","Pulmonary alveolus","Bronchoalveolar lavage","Immunology","Respiratory disease","Internal medicine","Anesthesia","Cytokine","Chemistry"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-06T13:38:21.470860Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}