{"doi":"10.4049/jimmunol.131.6.2903","title":"Thy-1 antigen is present on B and T lymphocytes of the Syrian hamster.","abstract":"<jats:title>Abstract</jats:title>\n               <jats:p>A widely used murine monoclonal antibody (mAb) to the Thy-1.2 allele and a highly absorbed xenoantiserum to hamster thymocytes bind to all thymocytes and a subpopulation of peripheral lymphoid cells of the Syrian hamster (Mesocricetus auratus). The mAb appears to detect the hamster Thy-1 homologue because hamster and mouse brain tissue each completely absorb the reactivity to hamster lymphocytes. Previous studies suggested that anti-Thy-1.2 identifies hamster T lymphocytes exclusively. Fluorescence analysis, however, demonstrates a large overlap of Thy-1.2+ and slg+ lymph node and spleen cells. Moreover, highly enriched (greater than 97%) Thy-1+ lymph node cells are greater than 50% slg+, give enhanced proliferative responses to LPS and anti-Ig in vitro, and reexpress normal amounts of slg 18 to 24 hr after Ig is removed from the cell surface. Thus, the hamster Thy-1 homologue is distributed not only on T cells but also on the majority of resting, peripheral B cells, and therefore cannot be utilized adequately as a T cell-specific marker in this species.</jats:p>","journal":"The Journal of Immunology","year":1983,"id":35722,"datarank":1.250899132870656,"base_score":2.8903717578961645,"endowment":2.8903717578961645,"self_citation_contribution":0.4335557636844247,"citation_network_contribution":0.8173433691862313,"self_endowment_contribution":0.4335557636844247,"citer_contribution":0.8173433691862313,"corpus_percentile":null,"corpus_rank":null,"citation_count":17,"citer_count":15,"citers_with_citation_signal":12,"citers_with_endowment":12,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":182400,"name":"J W Streilein","orcid":null,"position":1,"is_corresponding":false},{"id":182399,"name":"P L Witte","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":2.8903717578961645,"endowment":2.8903717578961645,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"6139401","pmcid":null,"openalex_id":"https://openalex.org/W1565833583","authors":[],"funders":[{"funder_name":"NCRR NIH HHS","grant_id":"RR01133-06","title":null},{"funder_name":"NCI NIH HHS","grant_id":"CA-09082","title":null}],"total_grants":2,"fwci":0.8915,"citation_percentile":0.7415622,"influential_citations":4,"citation_trend":[{"year":2016,"count":1}],"oa_status":"bronze","license":"https://academic.oup.com/pages/standard-publication-reuse-rights","oa_locations":[{"url":"https://journals.aai.org/jimmunol/article-pdf/131/6/2903/1021986/2903.pdf","host_type":"journal"},{"url":"https://journals.aai.org/jimmunol/article-pdf/131/6/2903/1021986/2903.pdf","host_type":"BRONZE"},{"url":"https://journals.aai.org/jimmunol/article-pdf/131/6/2903/1021986/2903.pdf","host_type":"publisher"},{"url":"https://academic.oup.com/jimmunol/article-pdf/131/6/2903/62797554/2903.pdf","host_type":"publisher"},{"url":"https://doi.org/10.4049/jimmunol.131.6.2903","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/6139401","host_type":"repository"}],"fields_of_study":["T-cell and B-cell Immunology","Immune Response and Inflammation","Chemokine receptors and signaling","Biology","Medicine"],"mesh_terms":["Animals","Antigens, Surface","Antilymphocyte Serum","B-Lymphocytes","Brain","Cross Reactions","Female","Goats","Cricetinae","Lymph Nodes","Mesocricetus","Receptors, Antigen, B-Cell","T-Lymphocytes","Thy-1 Antigens","Mice","Rats"],"keywords":["Hamster","Antigen","Biology","Immunology","Virology","Molecular biology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Life in Land"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-10T08:16:38.429848Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}