{"doi":"10.3892/ol.2018.9650","title":"MicroRNA‑183 and microRNA‑141 are potential risk factors for poor prognosis in patients with nasopharyngeal carcinoma","abstract":null,"journal":"Oncology Letters","year":2018,"id":645312,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":989030,"name":"Yujie Li","orcid":"0000-0002-0275-2797","position":1,"is_corresponding":false},{"id":1041655,"name":"Min Yu","orcid":"0000-0002-4885-8829","position":2,"is_corresponding":false},{"id":1680244,"name":"Junsheng Lian","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"MicroRNA‑183 and microRNA‑141 are potential risk factors for poor prognosis in patients with nasopharyngeal carcinoma","abstract":"This study investigated whether microRNA-183 and microRNA-141 in nasopharyngeal carcinoma (NPC) lesions are potential risk factors for poor prognosis. A total of 317 NPC patients admitted to Zhengzhou Central Hospital Affiliated to Zhengzhou University from January 2010 to March 2015 were included. Reverse transcription-quantitative PCR (RT-qPCR) was used to detect the expression of microRNA-183 and microRNA-141 in lesions and adjacent tissues, and the relationship between the microRNA-183 and microRNA-141 expression levels and prognosis was analyzed. The expression levels of microRNA-183 and microRNA-141 in lesions were significantly higher than those in adjacent tissues (p<0.05). Patients with distant metastasis had significantly higher expression levels of microRNA-183 and microRNA-141 than patients without distant metastasis (p<0.01). Patients with disease-free survival (DFS) <3 years showed significantly higher expression levels of microRNA-183 and microRNA-141 than those with DFS ≥3 years (p<0.01). NPC patients with high expression levels of microRNA-183 and microRNA-141 showed poor prognosis. MicroRNA-183 and microRNA-141 may play an important role in the distant metastasis of NPC, and have a great impact on prognosis.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"30655880","pmcid":"PMC6312981","openalex_id":"https://openalex.org/W30655880","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"gold","license":"cc-by-nc-nd","oa_locations":[{"url":"http://www.spandidos-publications.com/10.3892/ol.2018.9650/download","host_type":"publisher"},{"url":"https://dialnet.unirioja.es/servlet/tesis?codigo=915","host_type":"repository"},{"url":"http://europepmc.org/pmc/articles/PMC6312981","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6312981","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC6312981","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC6312981?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Cultural and political discourse analysis","Spanish Linguistics and Language Studies"],"mesh_terms":[],"keywords":["Philosophy","Humanities","Political science","Nasopharyngeal carcinoma","Prognosis","Distant Metastasis","Microrna-141","Microrna-183"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Reduced inequalities"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-09T04:41:54.289432Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}