{"doi":"10.36959/734/382","title":"The Utility of Spermidine Serum Levels as a Biomarker of Alzheimer's Disease a Pilot Study","abstract":"There is a close link between iron and polyamine biosynthesis and metabolism. In a recent study, we reported alterations in the serum levels of hepcidin and other iron-related proteins in Alzheimer's disease (AD) patients (Sternberg, et al., 2017). Based on these findings, this pilot study compared serum levels of one of the polyamines, Spermidine, between AD, mild cognitive impairment (MCI), and control subjects, correlating with the existing neuroimaging data.","journal":"Alzheimers Disease & Dementia","year":2021,"id":208289,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9542,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":794846,"name":"Rebecca Podolsky","orcid":null,"position":1,"is_corresponding":false},{"id":794847,"name":"Adam Nir","orcid":null,"position":2,"is_corresponding":false},{"id":794848,"name":"Yu Jihnhee","orcid":null,"position":3,"is_corresponding":false},{"id":794849,"name":"N Raphael","orcid":null,"position":4,"is_corresponding":false},{"id":794850,"name":"Halvorsen Stanley W","orcid":null,"position":5,"is_corresponding":false},{"id":794851,"name":"Quinn Joseph F.","orcid":null,"position":6,"is_corresponding":false},{"id":55003,"name":"Jeffrey Kaye","orcid":"0000-0002-9971-3478","position":7,"is_corresponding":false},{"id":794852,"name":"Kolb Channa","orcid":null,"position":8,"is_corresponding":false},{"id":794845,"name":"Sternberg Zohara","orcid":null,"position":0,"is_corresponding":true}],"reference_count":23,"raw_metadata":null,"created_at":"2026-07-18T23:51:53.662668Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}