{"doi":"10.3410/f.738515465.793578648","title":"Faculty Opinions recommendation of Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.","abstract":"Leucine Rich Repeat Kinase 2 (LRRK2) is the most commonly mutated gene in familial Parkinson's disease (PD) 1 and is also linked to its idiopathic form 2 . LRRK2 is proposed to function in membrane trafficking 3 and co-localizes with microtubules 4 . Despite LRRK2's fundamental importance for understanding and treating PD, there is limited structural information on it. Here we report the 3.5 structure of the catalytic half of LRRK2, and an atomic model of Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:","journal":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","year":2020,"id":132713,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9436,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":281189,"name":"Ahmet Yıldız","orcid":"0000-0003-4792-174X","position":0,"is_corresponding":true}],"reference_count":50,"raw_metadata":null,"created_at":"2026-07-18T23:16:14.071209Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}