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When such an immune complex (target antigen × antibody against the target antigen) with a slight antigen excess is administered, it evokes a corrective immune response by the production of the same antibody with the same specificity against the target antigen that is present in the immune complex (pre-determined immune response).</jats:p>","journal":"Vaccines","year":2018,"id":600559,"datarank":0.519860385419959,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"self_citation_contribution":0.519860385419959,"citation_network_contribution":0.0,"self_endowment_contribution":0.519860385419959,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":31,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1225308,"name":"Chad Cole","orcid":"0000-0002-3062-2850","position":1,"is_corresponding":false},{"id":1539717,"name":"Zoltan Kovacs","orcid":null,"position":2,"is_corresponding":false},{"id":1539718,"name":"Erno Kovacs","orcid":null,"position":3,"is_corresponding":false},{"id":1539719,"name":"Rene Lafreniere","orcid":null,"position":4,"is_corresponding":false},{"id":1539716,"name":"Arpad Barabas","orcid":"0000-0002-4238-9750","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"The Modified Vaccination Technique","abstract":"<jats:p>In addition to active and passive immunizations, there is a third method of immunization, the modified vaccination technique, which is based on injecting a combination of target antigens and antibodies against this antigen. The vaccine is essentially comprised of immune complexes with pre-determined immune-inducing components. When such an immune complex (target antigen × antibody against the target antigen) with a slight antigen excess is administered, it evokes a corrective immune response by the production of the same antibody with the same specificity against the target antigen that is present in the immune complex (pre-determined immune response).</jats:p>","is_dataset_classified":null,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"30577575","pmcid":"PMC6466438","openalex_id":"https://openalex.org/W2903752946","authors":[],"funders":[],"total_grants":0,"fwci":2.4669,"citation_percentile":0.92479989,"influential_citations":0,"citation_trend":[{"year":2017,"count":1},{"year":2020,"count":6},{"year":2021,"count":24}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://www.mdpi.com/2076-393X/7/1/1/pdf?version=1545364836","host_type":"journal"},{"url":"https://www.mdpi.com/2076-393X/7/1/1/pdf?version=1545364836","host_type":"publisher"},{"url":"https://www.mdpi.com/2076-393X/7/1/1/pdf","host_type":"publisher"},{"url":"https://doi.org/10.3390/vaccines7010001","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/30577575","host_type":"repository"},{"url":"https://doaj.org/article/5668704ab5cb4878b5e0b6a69facfd8b","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6466438","host_type":"repository"},{"url":"http://doi.org/10.3390/vaccines7010001","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC6466438","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC6466438?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["CAR-T cell therapy research","Monoclonal and Polyclonal Antibodies Research","Immunotherapy and Immune Responses"],"mesh_terms":[],"keywords":["Immune system","Antigen","Immunization","Vaccination","Immunology","Antibody","Virology","Medicine","immune complex","Antibody Information Transfer","Heymann Nephritis"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"doi"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-29T13:28:57.364017Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}