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This research emphasizes the need for the early monitoring of cytokines and targeted management strategies to mitigate the impact of COVID-19, especially among high-risk unvaccinated populations.</jats:p>","journal":"Pathogens","year":2025,"id":626514,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1620656,"name":"Khouloud Ayed","orcid":null,"position":1,"is_corresponding":false},{"id":1620657,"name":"Sara Zayati","orcid":null,"position":2,"is_corresponding":false},{"id":1620658,"name":"Rym Akrout","orcid":"0000-0003-0020-3775","position":3,"is_corresponding":false},{"id":1620659,"name":"Akram Dlala","orcid":null,"position":4,"is_corresponding":false},{"id":1620661,"name":"Amal Abouda","orcid":null,"position":5,"is_corresponding":false},{"id":1620663,"name":"Nesrine Zoghlami","orcid":null,"position":6,"is_corresponding":false},{"id":1620665,"name":"Halima Mahjoubi","orcid":null,"position":7,"is_corresponding":false},{"id":1620666,"name":"Iheb Labbane","orcid":null,"position":8,"is_corresponding":false},{"id":1620668,"name":"Asma Gati","orcid":"0000-0001-8507-0451","position":9,"is_corresponding":false},{"id":1620655,"name":"Ahmed Farhan","orcid":"0009-0005-0894-844X","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Optimizing Clinical Management of COVID-19: A Predictive Model for Unvaccinated Patients Admitted to ICU","abstract":"<jats:p>This study investigates the impact of immunological and clinical factors on COVID-19 outcomes among unvaccinated individuals. 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