{"doi":"10.3390/pathogens12020321","title":"T Cell Response to SARS-CoV-2 Coinfection and Comorbidities","abstract":"For the past three years, COVID-19 has become an increasing global health issue. Adaptive immune cells, especially T cells, have been extensively investigated in regard to SARS-CoV-2 infection. However, human health and T cell responses are also impacted by many other pathogens and chronic diseases. We have summarized T cell performance during SARS-CoV-2 coinfection with other viruses, bacteria, and parasites. Furthermore, we distinguished if those altered T cell statuses under coinfection would affect their clinical outcomes, such as symptom severity and hospitalization demand. T cell alteration in diabetes, asthma, and hypertension patients with SARS-CoV-2 infection was also investigated in our study. We have summarized whether changes in T cell response influence the clinical outcome during comorbidities.","journal":"Pathogens","year":2023,"id":369436,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9565,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":486872,"name":"Hao‐Yun Peng","orcid":"0000-0001-5151-590X","position":1,"is_corresponding":false},{"id":1128392,"name":"Aspen Pham","orcid":null,"position":2,"is_corresponding":false},{"id":1128393,"name":"Eber Villazana","orcid":null,"position":3,"is_corresponding":false},{"id":630571,"name":"Darby J. Ballard","orcid":"0000-0001-5766-851X","position":4,"is_corresponding":false},{"id":486870,"name":"Jugal Kishore Das","orcid":"0000-0002-4553-2196","position":5,"is_corresponding":false},{"id":486871,"name":"Anil Kumar","orcid":"0000-0002-7611-5918","position":6,"is_corresponding":false},{"id":486874,"name":"Xiaofang Xiong","orcid":"0000-0001-8276-4415","position":7,"is_corresponding":false},{"id":486875,"name":"Jianxun Song","orcid":"0000-0002-9734-6176","position":8,"is_corresponding":false},{"id":486869,"name":"Liqing Wang","orcid":"0009-0000-9896-3793","position":0,"is_corresponding":true}],"reference_count":105,"raw_metadata":null,"created_at":"2026-07-19T01:15:28.704894Z","pmid":"36839596","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}