{"doi":"10.3390/mi16111255","title":"Development and Validation of a Multimodal Wearable Belt for Abdominal Biosignal Monitoring with Application to Irritable Bowel Syndrome","abstract":"Visceral pain in Irritable Bowel Syndrome (IBS) is difficult to evaluate objectively due to its complex physiological nature and lack of reliable biomarkers. Given the complexity of IBS, a multimodal physiological monitoring approach, combining electrodermal activity (EDA), electrocardiogram (ECG), and surface electromyography (sEMG), offers a promising approach to capture the autonomic and muscular responses linked to visceral pain. However, no existing wearable device supports simultaneous EDA, ECG, and sEMG acquisition from the abdomen in a format suitable for long-term, real-world use. This study presents the development and validation of a novel wearable belt for concurrent ECG, sEMG, and EDA monitoring, with EDA measured at both the torso and wrist. The system was built using modified BITalino platforms with custom-fabricated reusable electrodes and Bluetooth connectivity for real-time smartphone display. Signal quality was validated against laboratory-grade systems in 20 healthy participants during a four-stage protocol involving cognitive, orthostatic, muscular, and combined stress tasks. Time and frequency-domain analyses showed high correlations and comparable spectral features across all modalities. The belt maintained stable skin contact even during movement-intensive tasks. By enabling anatomically targeted, multimodal data acquisition, this wearable system supports real-world visceral pain assessment in IBS and is ready for deployment in ambulatory and home-based monitoring scenarios.","journal":"Micromachines","year":2025,"id":548202,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9559,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1441417,"name":"S Senthur Raja Pandian","orcid":"0009-0000-2640-655X","position":1,"is_corresponding":false},{"id":920732,"name":"Riley McNaboe","orcid":"0000-0002-2211-7475","position":2,"is_corresponding":false},{"id":1441874,"name":"Thuany De Carvalho Lachos","orcid":null,"position":3,"is_corresponding":false},{"id":1441875,"name":"Daniel Octavio Lantigua","orcid":null,"position":4,"is_corresponding":false},{"id":328565,"name":"Hugo F. Posada–Quintero","orcid":"0000-0003-4514-4772","position":5,"is_corresponding":false},{"id":1441416,"name":"Amir Mohammad Karimi Forood","orcid":"0009-0006-4489-5960","position":0,"is_corresponding":true}],"reference_count":47,"raw_metadata":null,"created_at":"2026-07-19T02:53:58.530220Z","pmid":"41302773","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}