{"doi":"10.3390/mi14030680","title":"Chronic Stability of Local Field Potentials Using Amorphous Silicon Carbide Microelectrode Arrays Implanted in the Rat Motor Cortex","abstract":"Implantable microelectrode arrays (MEAs) enable the recording of electrical activity of cortical neurons, allowing the development of brain-machine interfaces. However, MEAs show reduced recording capabilities under chronic conditions, prompting the development of novel MEAs that can improve long-term performance. Conventional planar, silicon-based devices and ultra-thin amorphous silicon carbide (a-SiC) MEAs were implanted in the motor cortex of female Sprague-Dawley rats, and weekly anesthetized recordings were made for 16 weeks after implantation. The spectral density and bandpower between 1 and 500 Hz of recordings were compared over the implantation period for both device types. Initially, the bandpower of the a-SiC devices and standard MEAs was comparable. However, the standard MEAs showed a consistent decline in both bandpower and power spectral density throughout the 16 weeks post-implantation, whereas the a-SiC MEAs showed substantially more stable performance. These differences in bandpower and spectral density between standard and a-SiC MEAs were statistically significant from week 6 post-implantation until the end of the study at 16 weeks. These results support the use of ultra-thin a-SiC MEAs to develop chronic, reliable brain-machine interfaces.","journal":"Micromachines","year":2023,"id":339455,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":16,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9538,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":717073,"name":"Justin Abbott","orcid":"0000-0003-1514-3357","position":1,"is_corresponding":false},{"id":698326,"name":"Joshua O. Usoro","orcid":"0000-0002-4596-663X","position":2,"is_corresponding":false},{"id":1073050,"name":"Yupeng Wu","orcid":"0009-0001-4717-5217","position":3,"is_corresponding":false},{"id":1073051,"name":"Pegah Haghighi","orcid":"0009-0007-1427-2129","position":4,"is_corresponding":false},{"id":717590,"name":"Rahul Radhakrishna","orcid":null,"position":5,"is_corresponding":false},{"id":698327,"name":"Brandon S. Sturgill","orcid":"0000-0002-8161-9723","position":6,"is_corresponding":false},{"id":1073447,"name":"Shido Nakajima","orcid":null,"position":7,"is_corresponding":false},{"id":917084,"name":"Teresa Thai","orcid":null,"position":8,"is_corresponding":false},{"id":400184,"name":"Joseph J. Pancrazio","orcid":"0000-0001-8276-3690","position":9,"is_corresponding":false},{"id":424452,"name":"Stuart F. Cogan","orcid":"0000-0001-6316-3032","position":10,"is_corresponding":false},{"id":766833,"name":"Ana G. Hernández-Reynoso","orcid":"0000-0003-2961-2759","position":11,"is_corresponding":false},{"id":1073049,"name":"Eleanor N. Jeakle","orcid":"0009-0009-8714-3517","position":0,"is_corresponding":true}],"reference_count":66,"raw_metadata":null,"created_at":"2026-07-19T01:10:45.048445Z","pmid":"36985087","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}