{"doi":"10.3390/md13095882","title":"Polysaccharide Constituents of Three Types of Sea Urchin Shells and Their Anti-Inflammatory Activities","abstract":"<jats:p>As a source of potent anti-inflammatory traditional medicines, the quantitative chromatographic fingerprints of sea urchin shell polysaccharides were well established via pre-column derivatization high performance liquid chromatography (HPLC) analysis. Based on the quantitative results, the content of fucose and glucose could be used as preliminary distinguishing indicators among three sea urchin shell species. Besides, the anti-inflammatory activities of the polysaccharides from sea urchin shells and their gonads were also determined. The gonad polysaccharide of Anthocidaris crassispina showed the most potent anti-inflammatory activity among all samples tested.</jats:p>","journal":"Marine Drugs","year":2015,"id":30365,"datarank":1.250355163717078,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"self_citation_contribution":0.519860385419959,"citation_network_contribution":0.7304947782971188,"self_endowment_contribution":0.519860385419959,"citer_contribution":0.7304947782971188,"corpus_percentile":null,"corpus_rank":null,"citation_count":31,"citer_count":31,"citers_with_citation_signal":27,"citers_with_endowment":27,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":165120,"name":"Xiaohui Shang","orcid":null,"position":1,"is_corresponding":false},{"id":165121,"name":"Qi Dong","orcid":null,"position":2,"is_corresponding":false},{"id":165122,"name":"Shuang Wang","orcid":null,"position":3,"is_corresponding":false},{"id":165123,"name":"Xiaoyu Liu","orcid":null,"position":4,"is_corresponding":false},{"id":28627,"name":"Heng Zheng","orcid":"0000-0002-6930-6783","position":5,"is_corresponding":false},{"id":165124,"name":"Xiaoling Lu","orcid":null,"position":6,"is_corresponding":false},{"id":165119,"name":"Heng Jiao","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"26389925","pmcid":"PMC4584359","openalex_id":"https://openalex.org/W2140973468","authors":[],"funders":[{"funder_name":"the National Hi-tech R&amp;D Program","grant_id":"SS2013AA093002","title":null}],"total_grants":1,"fwci":2.8575,"citation_percentile":0.90268389,"influential_citations":0,"citation_trend":[{"year":2016,"count":2},{"year":2017,"count":3},{"year":2019,"count":5},{"year":2021,"count":2},{"year":2022,"count":3},{"year":2023,"count":2},{"year":2024,"count":3},{"year":2025,"count":11}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://www.mdpi.com/1660-3397/13/9/5882/pdf?version=1442393055","host_type":"journal"},{"url":"https://www.mdpi.com/1660-3397/13/9/5882/pdf?version=1442393055","host_type":"GOLD"},{"url":"https://www.mdpi.com/1660-3397/13/9/5882/pdf?version=1442393055","host_type":"publisher"},{"url":"https://www.mdpi.com/1660-3397/13/9/5882/pdf","host_type":"publisher"},{"url":"https://doi.org/10.3390/md13095882","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/26389925","host_type":"repository"},{"url":"https://doaj.org/article/f724731b54de417f91de937bf1192375","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4584359","host_type":"repository"},{"url":"http://dx.doi.org/10.3390/md13095882","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC4584359","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC4584359?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Seaweed-derived Bioactive Compounds","Echinoderm biology and ecology","Marine Sponges and Natural Products","Biology","Medicine","Environmental Science","Animal Shells","Animals","Anti-Inflammatory Agents","Cell Line","Cell Survival","Inflammation","Lipopolysaccharides","Macrophages","Mice","Polysaccharides","Sea Urchins"],"mesh_terms":["Animals","Anti-Inflammatory Agents","Cell Line","Cell Survival","Inflammation","Lipopolysaccharides","Macrophages","Polysaccharides","Sea Urchins","Mice","Animal Shells"],"keywords":["Sea urchin","Fucose","Polysaccharide","Derivatization","High-performance liquid chromatography","Chemistry","Chromatography","Anti-inflammatory","Biology","Biochemistry","Ecology","Galactose","High performance liquid chromatography","Quantitative determination"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Life below water"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-09T02:21:32.992402Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}