{"doi":"10.3390/jof8101101","title":"The Effects of Sex and Strain on Pneumocystis murina Fungal Burdens in Mice","abstract":"Many preclinical studies of infectious diseases have neglected experimental designs that evaluate potential differences related to sex with a concomitant over-reliance on male model systems. Hence, the NIH implemented a monitoring system for sex inclusion in preclinical studies. Methods: Per this mandate, we examined the lung burdens of Pneumocystis murina infection in three mouse strains in both male and female animals at early, mid, and late time points. Results: Females in each strain had higher infection burdens compared to males at the later time points. Conclusion: Females should be included in experimental models studying Pneumocystis spp.","journal":"Journal of Fungi","year":2022,"id":295971,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9168,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":538393,"name":"Alan Ashbaugh","orcid":null,"position":1,"is_corresponding":false},{"id":982724,"name":"Keeley Hendrix","orcid":null,"position":2,"is_corresponding":false},{"id":311304,"name":"Margaret S. Collins","orcid":"0009-0006-3842-2913","position":3,"is_corresponding":false},{"id":312137,"name":"Aleksey Porollo","orcid":"0000-0002-3202-5099","position":4,"is_corresponding":false},{"id":399800,"name":"Melanie T. Cushion","orcid":"0000-0001-6621-2784","position":5,"is_corresponding":false},{"id":982181,"name":"Nikeya L. Macioce-Tisdale","orcid":"0000-0002-5919-129X","position":0,"is_corresponding":true}],"reference_count":15,"raw_metadata":null,"created_at":"2026-07-19T00:31:12.531553Z","pmid":"36294666","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}