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In this review, the current knowledge on the multifaceted role of SA in ER stress and UPR is summarized in model plants and crops to gain a better understanding of SA-regulated processes at the physiological, biochemical, and molecular levels.</jats:p>","journal":"International Journal of Molecular Sciences","year":2019,"id":609335,"datarank":0.6010999777848708,"base_score":4.007333185232471,"endowment":4.007333185232471,"self_citation_contribution":0.6010999777848708,"citation_network_contribution":0.0,"self_endowment_contribution":0.6010999777848708,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":54,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1566114,"name":"Zalán Czékus","orcid":null,"position":1,"is_corresponding":false},{"id":1566115,"name":"Irma Tari","orcid":null,"position":2,"is_corresponding":false},{"id":1566116,"name":"Attila Ördög","orcid":null,"position":3,"is_corresponding":false},{"id":1566113,"name":"Péter Poór","orcid":"0000-0002-4539-6358","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"The Multifaceted Roles of Plant Hormone Salicylic Acid in Endoplasmic Reticulum Stress and Unfolded Protein Response","abstract":"<jats:p>Different abiotic and biotic stresses lead to the accumulation of unfolded and misfolded proteins in the endoplasmic reticulum (ER), resulting in ER stress. In response to ER stress, cells activate various cytoprotective responses, enhancing chaperon synthesis, protein folding capacity, and degradation of misfolded proteins. These responses of plants are called the unfolded protein response (UPR). ER stress signaling and UPR can be regulated by salicylic acid (SA), but the mode of its action is not known in full detail. In this review, the current knowledge on the multifaceted role of SA in ER stress and UPR is summarized in model plants and crops to gain a better understanding of SA-regulated processes at the physiological, biochemical, and molecular levels.</jats:p>","is_dataset_classified":null,"base_score":4.007333185232471,"endowment":4.007333185232471,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"31766401","pmcid":"PMC6928836","openalex_id":"https://openalex.org/W2991046320","authors":[],"funders":[{"funder_name":"Nemzeti Kutatási, Fejlesztési és Innovaciós Alap","grant_id":"OTKA PD112855","title":null},{"funder_name":"Nemzeti Kutatási, Fejlesztési és Innovaciós Alap","grant_id":"NKFIH FK 124871","title":null},{"funder_name":"New National Excellence Program of the Ministry of Human Capacities","grant_id":"UNKP-18-3-I-SZTE-17 and UNKP-19-4-SZTE-86","title":null},{"funder_name":"János Bolyai Research Scholarship of the Hungarian Academy of Sciences","grant_id":"BO/00743/19/8","title":null}],"total_grants":4,"fwci":2.9467,"citation_percentile":0.9116351,"influential_citations":0,"citation_trend":[{"year":2020,"count":7},{"year":2021,"count":9},{"year":2022,"count":13},{"year":2023,"count":11},{"year":2024,"count":8},{"year":2025,"count":2},{"year":2026,"count":4}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://www.mdpi.com/1422-0067/20/23/5842/pdf?version=1574399824","host_type":"journal"},{"url":"https://www.mdpi.com/1422-0067/20/23/5842/pdf?version=1574399824","host_type":"publisher"},{"url":"https://www.mdpi.com/1422-0067/20/23/5842/pdf","host_type":"publisher"},{"url":"https://doi.org/10.3390/ijms20235842","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/31766401","host_type":"repository"},{"url":"https://doaj.org/article/65c4768f0c2441f7b747779324e6dbac","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6928836","host_type":"repository"},{"url":"http://dx.doi.org/10.3390/ijms20235842","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC6928836","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC6928836?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Endoplasmic Reticulum Stress and Disease","Autophagy in Disease and Therapy","Carbon and Quantum Dots Applications","Arabidopsis","Arabidopsis Proteins","Endoplasmic Reticulum","Endoplasmic Reticulum Stress","Models, Biological","Plant Growth Regulators","Salicylic Acid","Signal Transduction","Unfolded Protein Response"],"mesh_terms":["Endoplasmic Reticulum","Models, Biological","Plant Growth Regulators","Signal Transduction","Arabidopsis","Salicylic Acid","Arabidopsis Proteins","Unfolded Protein Response","Endoplasmic Reticulum Stress"],"keywords":["Endoplasmic reticulum","Unfolded protein response","Protein folding","Salicylic acid","Cell biology","Tunicamycin","Folding (DSP implementation)","Abiotic stress","Chemistry","Endoplasmic-reticulum-associated protein degradation","Biochemistry","Biology","Binding protein","Systemic acquired resistance","Cell death","Pathogenesis-related Genes"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"doi"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-31T06:22:21.744298Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}