{"doi":"10.3390/cancers16081606","title":"Seroprevalence of SARS-CoV-2 and Hepatitis B Virus Coinfections among Ethiopians with Acute Leukemia","abstract":"SARS-CoV-2 and blood-borne viral coinfections are well reported. Nevertheless, little is known regarding the seroprevalence of SARS-CoV-2 and coinfection with blood-borne viruses in hematologic malignancy patients in Ethiopia. We aimed to assess the seroprevalence of SARS-CoV-2 and associated infections with hepatitis B and other viruses among adolescent and adult acute leukemia patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. A cross-sectional study was conducted from July 2020 to June 2021. Blood samples were tested for the presence of anti-SARS-CoV-2, HBV, HCV, and HIV with ELISA kits and occult hepatitis B infection with a real-time polymerase chain reaction assay. Out of a total 110 cases, the SARS-CoV-2 seroprevalence was 35.5%. The prevalence showed a significant increment from July 2020 to the end of June 2021 (p = 0.015). In 22.7% and 2.7% of leukemia cases, HBV and HIV, respectively, were detected. No HCV was identified. The rate of SARS-CoV-2 coinfection with HBV and HIV was 28% (11/39) and 2.6% (1/39), respectively; however, there was no statistically significant association between SARS-CoV-2 seropositivity with HBV and HIV (p > 0.05). There is a need for viral screening in leukemia cases to monitor infections and inform management.","journal":"Cancers","year":2024,"id":478661,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9649,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":750156,"name":"Balako Gumi","orcid":"0000-0002-2049-4955","position":1,"is_corresponding":false},{"id":746206,"name":"Aster Tsegaye","orcid":"0000-0002-9026-4629","position":2,"is_corresponding":false},{"id":1317719,"name":"Ziyada Rahimeto","orcid":null,"position":3,"is_corresponding":false},{"id":935653,"name":"Dessalegn Fentahun","orcid":null,"position":4,"is_corresponding":false},{"id":1317720,"name":"Fozia Ibrahim","orcid":null,"position":5,"is_corresponding":false},{"id":1141604,"name":"Abdulaziz Abubeker","orcid":null,"position":6,"is_corresponding":false},{"id":1317423,"name":"Amha Gebremedhin","orcid":"0000-0003-3010-2860","position":7,"is_corresponding":false},{"id":809385,"name":"Tesfaye Gelanew","orcid":"0000-0002-0696-3786","position":8,"is_corresponding":false},{"id":754386,"name":"Rawleigh Howe","orcid":"0000-0002-4001-5456","position":9,"is_corresponding":false},{"id":1317422,"name":"Jemal Alemu","orcid":"0000-0003-3850-7328","position":0,"is_corresponding":true}],"reference_count":41,"raw_metadata":null,"created_at":"2026-07-19T02:06:46.330532Z","pmid":"38672687","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}