{"doi":"10.3389/frym.2022.783791","title":"Getting to the Bottom of Cancer Treatment Pain","abstract":"What would you do if you had a disease, but the treatment made you feel even more sick? Chemotherapy drugs are a common tool used to treat cancer, but they have negative side effects. These drugs change the cells in our body leading to pain or burning or numbness in the fingers and toes. These drugs also impact cancer patients’ lives and limits their much-needed chemotherapy treatment. Our research investigated how cells and their DNA contribute to this pain. When we are hurt, certain cells send signals that create pain to help us heal. Studying these cell’s DNA could help us learn why cancer treatment pain occurs, and how we can possibly prevent it. While comparing normal mice to mice that have had their DNA changed, we explore how cancer treatment pain develops, and how certain cells are affected by chemotherapy.","journal":"Frontiers for Young Minds","year":2023,"id":402328,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9519,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1180190,"name":"Erica J. Pemberton","orcid":null,"position":1,"is_corresponding":false},{"id":257963,"name":"Michael D. Burton","orcid":"0000-0002-0628-824X","position":2,"is_corresponding":false},{"id":1180189,"name":"Smrithi Upadhyayula","orcid":null,"position":0,"is_corresponding":true}],"reference_count":3,"raw_metadata":null,"created_at":"2026-07-19T01:20:27.903246Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}