{"doi":"10.3389/fragi.2022.1016274","title":"Editorial: “Obesity, Metabolism and the immune system”","abstract":"and distinct features of aging and obesity, two conditions characterized by chronic, low-grade systemic 55 inflammation and dysfunctional immunity and associated to several clinical problems, including reduced 56 vaccine responses. The cited work favors the hypothesis that obesity is is a state of accelerated immune 57 aging.The original research paper \"Altered nutrient uptake causes mitochondrial dysfunction in senescent CD8 + Taken together, this series extends the current understanding of immunometabolism in aging and 78 obesity, while identifying new mechanisms foundational to the interrelationship between these conditions.The editors are optimistic that the assembled series will spark more research into actionable changes in 80 immunometabolism that support the clinical problems triggered by these naturally occurring events.","journal":"Frontiers in Aging","year":2022,"id":304290,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9116,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":110425,"name":"Leena P. Bharath","orcid":"0000-0003-2259-0104","position":1,"is_corresponding":false},{"id":110442,"name":"Barbara S. Nikolajczyk","orcid":"0000-0001-5647-5740","position":2,"is_corresponding":false},{"id":259827,"name":"Daniela Frasca","orcid":"0000-0002-9816-6679","position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-19T00:32:32.651796Z","pmid":"36160605","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}