{"doi":"10.3389/fphys.2022.980674","title":"Editorial: Role of mitochondria-associated non-coding RNAs in intracellular communication","abstract":"Once considered solely as the powerhouse of eukaryotic cells, the mitochondrion is now known to be a hub for several other important cellular processes such as apoptosis, calcium homeostasis, regulation of innate immunity, amino acid metabolism, stem cell regulation and the cellular regulome, among others Some of these functions are accounted for by the minimal circular 16,569-bp genome of human mitochondria (mtDNA), which contains the genes for 2 rRNAs, 22 tRNAs and 13 polypeptides However, most mitochondrial proteins are nuclearencoded and imported from the cytosol Lately, there is increasing evidence of bidirectional communication between mitochondria and the nucleus, coordinating multiple cellular functions This connection, nonetheless, is not limited to mitochondrial import of nuclear-encoded proteins and export of metabolites, but has also been shown to involve noncoding RNAs (ncRNAs) connecting both cellular compartments Long noncoding RNAs (lncRNAs), as well as microRNAs (miRNAs) have been found inside mitochondria, both originating from the mtDNA These mitochondria-associated ncRNAs have been shown to participate in intracellular communication, not only with the nucleus, but also with other","journal":"Frontiers in Physiology","year":2022,"id":304077,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9255,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":996482,"name":"Éric Barrey","orcid":"0000-0001-7691-8705","position":1,"is_corresponding":false},{"id":560785,"name":"Eleonora Leucci","orcid":"0000-0002-2898-748X","position":2,"is_corresponding":false},{"id":643064,"name":"Nina Entelis","orcid":"0000-0002-7915-5528","position":3,"is_corresponding":false},{"id":351479,"name":"John M. Hollander","orcid":"0000-0001-5724-694X","position":4,"is_corresponding":false},{"id":381516,"name":"Samarjit Das","orcid":"0000-0002-4377-2823","position":5,"is_corresponding":false},{"id":996481,"name":"Verónica A. Burzio","orcid":"0000-0002-6491-4640","position":0,"is_corresponding":true}],"reference_count":14,"raw_metadata":null,"created_at":"2026-07-19T00:32:28.468841Z","pmid":"36072845","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}