{"doi":"10.3389/fped.2024.1349102","title":"Clinically defining the opioid-exposed birthing person and infant as a dyad to support bedside care, surveillance, and research","abstract":"Introduction: An increased incidence of maternal opioid use disorder (OUD) and neonatal abstinence syndrome (NAS) has prompted recommendations supporting a dyadic approach to care for birthing persons and their infants. However, there are no consensus guidelines outlining how the dyad is clinically defined. Methods: To examine how the opioid-exposed birthing person-infant dyad has been defined for purposes of data collection and research, a literature review applying the RAND/UCLA Appropriateness Method was conducted. Results: The search yielded 320 abstracts, with 110 articles identified as having a dyadic focus. While no articles included a specific definition for the dyad, 33 (30%) contained a descriptive reference to the birthing person-infant dyad. Thematic analysis revealed eight recurring elements characteristic of the dyad: (1) engagement, (2) communication, (3) bonding, (4) attachment, (5) mutual responsiveness, (6) reciprocity, (7) synchrony, and (8) attunement. Integrating these elements revealed the interactional relationship between the opioid-exposed birthing person and infant as the foundational principle that defines the dyad. Discussion: This definition shifts the focus of the opioid-exposed dyad from two individual patient populations to an interactional relationship that has broad applicability for clinical use, public health data collection, and research considerations.","journal":"Frontiers in Pediatrics","year":2024,"id":467940,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9586,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":593540,"name":"Jonathan M. Davis","orcid":"0000-0001-5209-9768","position":1,"is_corresponding":false},{"id":1300512,"name":"David Goldstein","orcid":"0000-0001-6142-3291","position":2,"is_corresponding":false},{"id":1300513,"name":"Matthew Grossman","orcid":"0000-0002-3596-8543","position":3,"is_corresponding":false},{"id":707888,"name":"Lauren M. Jansson","orcid":"0000-0003-2708-6142","position":4,"is_corresponding":false},{"id":314056,"name":"Mishka Terplan","orcid":"0000-0002-2489-2942","position":5,"is_corresponding":false},{"id":471611,"name":"Hendrée E. Jones","orcid":"0000-0001-6180-8642","position":6,"is_corresponding":false},{"id":707887,"name":"Shahla M. Jilani","orcid":"0000-0001-5089-1129","position":0,"is_corresponding":true}],"reference_count":27,"raw_metadata":null,"created_at":"2026-07-19T02:05:15.025255Z","pmid":"38774300","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}