{"doi":"10.3389/fnut.2023.1153399","title":"Dynapenic abdominal obesity and susceptibility to fall: a prospective analysis of the Osteoarthritis Initiative","abstract":"Background The prediction of the risk of falling remains a challenge in geriatric medicine and the identification of new potential reversible risk factors is a public health priority. In this study, we aim to investigate the association between DAO (dynapenic abdominal obesity) and incident falls in a large sample of people with knee OA (osteoarthritis) or at high risk for this condition, over 8 years of follow-up. Methods DAO was defined using a waist circumference more than 102 cm in men and 88 cm in women and a concomitant presence of dynapenia, defined as a time over 15 s in the five times chair stands time. Falls, during follow-up, were recorded using self-reported information in the previous year. A logistic binary regression analysis was run, adjusted for potential confounders at the baseline, reporting the data as odds ratios (ORs) with their 95% confidence intervals (CIs). Results Overall, 3,844 subjects were included, majority of whom had abdominal obesity. Across the 8 years of follow-up, 2,695 participants fell vs. 1,149 not reporting any fall. Taking those without DAO as reference, the presence of only dynapenia was not associated with risk of falls (OR = 1.18;95%CI: 0.73–1.91; p = 0.50), whilst the presence of abdominal obesity (OR = 1.30; 95%CI: 1.09–1.56; p = 0.004) and DAO (OR = 1.31; 95%CI:1.01–1.73; p = 0.04) were significantly associated with a higher risk of incident falls. Conclusion DAO significantly increased risk of falls as well as the presence of abdominal obesity.","journal":"Frontiers in Nutrition","year":2023,"id":365497,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9675,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":105393,"name":"Ai Koyanagi","orcid":"0000-0002-9565-5004","position":1,"is_corresponding":false},{"id":1048727,"name":"Pınar Soysal","orcid":"0000-0002-6042-1718","position":2,"is_corresponding":false},{"id":1048728,"name":"Francesco Bolzetta","orcid":"0000-0003-2930-4991","position":3,"is_corresponding":false},{"id":674867,"name":"Ligia J. Domínguez","orcid":"0000-0003-1466-8610","position":4,"is_corresponding":false},{"id":620314,"name":"Mario Barbagallo","orcid":"0000-0002-1349-6530","position":5,"is_corresponding":false},{"id":674865,"name":"Shaun Sabico","orcid":"0000-0002-5248-2350","position":6,"is_corresponding":false},{"id":674864,"name":"Nasser M. Al‐Daghri","orcid":"0000-0001-5472-1725","position":7,"is_corresponding":false},{"id":681,"name":"Lee Smith","orcid":"0000-0002-5340-9833","position":8,"is_corresponding":false},{"id":687,"name":"Nicola Veronese","orcid":"0000-0002-9328-289X","position":0,"is_corresponding":true}],"reference_count":30,"raw_metadata":null,"created_at":"2026-07-19T01:14:46.760245Z","pmid":"37215209","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}