{"doi":"10.3389/fgene.2022.928335","title":"Editorial: RNA-Mediated Epigenetic and Transcriptional Regulation","abstract":"RNA plays major regulatory roles in many processes beyond transcription, including protein complex formation, maintenance of genomic stability, and establishment of higher-order cellular structures via phase separation. Accordingly, regulation of RNA abundance, processing, and modification can have a profound impact on cellular and organismal biology. In recent years, significant progress has been made to decipher the complex molecular details and functional interplay between RNA and regulatory processes have begun to emerge. These studies have shed light on how perturbation to these mechanisms can yield aberrant biology, including formation of disease states such as cancers. In this Research Topic \"RNA-Mediated Epigenetic and Transcriptional Regulation,\" several articles highlight the importance of RNA-mediated regulation in different pathological contexts such as cancers and retinal degeneration, and developmental/adaptation processes such as sperm development, resistance to pathogens, and adaptation to cold. Altogether, this Research Topic further highlights the importance of RNA as an effector molecule in biology and underscores its biochemical versatility as a regulatory molecule.","journal":"Frontiers in Genetics","year":2022,"id":301393,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9474,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":811660,"name":"Yicheng Long","orcid":"0000-0003-4231-2136","position":1,"is_corresponding":false},{"id":795232,"name":"Mo Motamedi","orcid":"0000-0002-2031-6155","position":2,"is_corresponding":false},{"id":917606,"name":"A. Rasim Barutcu","orcid":"0000-0002-4838-8695","position":0,"is_corresponding":true}],"reference_count":3,"raw_metadata":null,"created_at":"2026-07-19T00:32:02.193874Z","pmid":"35734435","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}