{"doi":"10.3389/fepid.2023.1054108","title":"Epidemiology of chronic multimorbidity and temporary migration in a rural South African community in health transition: A cross-sectional population-based analysis","abstract":"Introduction: In sub-Saharan African settings, the increasing non-communicable disease mortality is linked to migration, which disproportionately exposes sub-populations to risk factors for co-occurring HIV and NCDs. Methods: We examined the prevalence, patterns, and factors associated with two or more concurrent diagnoses of chronic diseases (i.e., multimorbidity) among temporary within-country migrants. Employing a cross-sectional design, our study sample comprised 2144 residents and non-residents 18-40 years interviewed and with measured biomarkers in 2018 in Wave 1 of the Migrant Health Follow-up Study (MHFUS), drawn from the Agincourt Health and Demographic Surveillance System (AHDSS) in rural north-eastern South Africa. We used modified Poisson regression models to estimate the association between migration status and prevalent chronic multimorbidity conditional on age, sex, education, and healthcare utilisation. Results: Overall, 301 participants (14%; 95% CI 12.6-15.6), median age 31 years had chronic multimorbidity. Multimorbidity was more prevalent among non-migrants (14.6%; 95% CI 12.8-16.4) compared to migrants (12.8%; 95% CI 10.3-15.7). Non-migrants also had the greatest burden of dual-overlapping chronic morbidities, such as HIV-obesity 5.7%. Multimorbidity was 2.6 times as prevalent (PR 2.65. 95% CI 2.07-3.39) among women compared to men. Among migrants, men, and individuals with secondary or tertiary education manifested lower prevalence of two or more conditions. Discussion: In a rural community with colliding epidemics, we found low but significant multimorbidity driven by a trio of conditions: HIV, hypertension, and obesity. Understanding the multimorbidity burden associated with early adulthood exposures, including potential protective factors (i.e., migration coupled with education), is a critical first step towards improving secondary and tertiary prevention for chronic disease among highly mobile marginalised sub-populations.","journal":"Frontiers in Epidemiology","year":2023,"id":370888,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8971,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":896424,"name":"Carren Ginsburg","orcid":"0000-0002-8391-8268","position":1,"is_corresponding":false},{"id":443436,"name":"Chodziwadziwa Kabudula","orcid":"0000-0002-5867-0336","position":2,"is_corresponding":false},{"id":1130208,"name":"Rachel R. Yorlets","orcid":"0000-0002-0986-5444","position":3,"is_corresponding":false},{"id":559587,"name":"Pedzisai Ndagurwa","orcid":"0000-0001-5628-4901","position":4,"is_corresponding":false},{"id":896425,"name":"Sadson Harawa","orcid":"0000-0001-5887-5094","position":5,"is_corresponding":false},{"id":529909,"name":"Mark N. Lurie","orcid":"0000-0002-3153-1715","position":6,"is_corresponding":false},{"id":24994,"name":"Stephen T. McGarvey","orcid":"0000-0003-1233-6970","position":7,"is_corresponding":false},{"id":443314,"name":"Stephen Tollman","orcid":"0000-0003-0744-7588","position":8,"is_corresponding":false},{"id":500925,"name":"Mark Collinson","orcid":"0000-0002-8205-7099","position":9,"is_corresponding":false},{"id":1121645,"name":"Michael J. White","orcid":"0000-0001-9953-2258","position":10,"is_corresponding":false},{"id":277339,"name":"F. Xavier Gómez‐Olivé","orcid":"0000-0002-4876-0848","position":11,"is_corresponding":false},{"id":701785,"name":"Armstrong Dzomba","orcid":"0000-0002-4242-6312","position":0,"is_corresponding":true}],"reference_count":54,"raw_metadata":null,"created_at":"2026-07-19T01:15:41.237096Z","pmid":"38455922","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}