{"doi":"10.3389/fcell.2022.1054774","title":"Editorial: Visualization of molecular dynamics in live cells by fluorescent protein-based biosensors","abstract":"Cells continuously respond to a variety of stimulations, such as extracellular ligands, cell-cell interactions, and mechanical signals. These extracellular signals are received by membrane receptors, including ion channels, receptor tyrosine kinases (RTKs), G protein-coupled receptors (GPCRs), integrins, cadherins, and other adhesion molecules They are translated and transferred into the cells through signaling pathways, for example, kinases and phosphatases, second messengers such as cAMP and Ca 2+ , small GTPases, and transcription factors. The spatiotemporal interactions of these signaling molecules control complex cellular processes such as differentiation, cell migration, proliferation, and survival. Genetically encodable fluorescent protein (FP)-based biosensors have been developed for the real-time monitoring of molecular dynamics with the high spatiotemporal resolution, and applied to understand underlying mechanisms of complex cellular processes (Zacharias et al.,","journal":"Frontiers in Cell and Developmental Biology","year":2022,"id":312348,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9544,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":254303,"name":"Yingxiao Wang","orcid":"0000-0003-0265-326X","position":1,"is_corresponding":false},{"id":667819,"name":"Jihye Seong","orcid":"0000-0001-8450-3315","position":0,"is_corresponding":true}],"reference_count":7,"raw_metadata":null,"created_at":"2026-07-19T00:33:36.072096Z","pmid":"36313544","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}