{"doi":"10.3389/facou.2023.1326759","title":"Integrating ultrasonic neuromodulation with fiber photometry","abstract":"Ultrasound has been used to modulate neural activity in rodents and primates; however, combining ultrasound stimulation with in vivo imaging in freely moving animals has been challenging. Here, we design and validate a transducer to overcome these challenges in the rodent. We develop a head-mounted ultrasound transducer that can be combined with a fiber photometry system. This combination allows us to monitor ultrasound-evoked responses in striatal neurons in awake and freely moving animals. Together, this system allows for a high-resolution analysis of ultrasound-evoked biology at the level of both neural circuits and behavior in freely moving animals, critical to providing a mechanistic understanding of ultrasound neuromodulation.","journal":"Frontiers in Acoustics","year":2023,"id":415213,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9573,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":559087,"name":"Uri Magaram","orcid":"0000-0001-8324-0437","position":1,"is_corresponding":false},{"id":559088,"name":"Janki Patel","orcid":"0000-0002-8140-9347","position":2,"is_corresponding":false},{"id":415577,"name":"James Friend","orcid":"0000-0003-0416-2165","position":3,"is_corresponding":false},{"id":559094,"name":"Sreekanth H. Chalasani","orcid":"0000-0003-2522-8338","position":4,"is_corresponding":false},{"id":559092,"name":"Aditya Vasan","orcid":"0000-0002-6329-0397","position":0,"is_corresponding":true}],"reference_count":59,"raw_metadata":null,"created_at":"2026-07-19T01:22:08.814145Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}