{"doi":"10.33552/accs.2024.03.000571","title":"Rasburicase Induced Hemolysis in A Patient with Undiagnosed Glucose 6 Phosphate Dehydrogenase (G6PD) Deficiency","abstract":null,"journal":"Archives of Clinical Case Studies","year":2024,"id":646350,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1683453,"name":"Lorie Ann Foster","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Rasburicase Induced Hemolysis in A Patient with Undiagnosed Glucose 6 Phosphate Dehydrogenase (G6PD) Deficiency","abstract":"Rasburicase is a recombinant urate oxidase effective in lowering uric acid accumulation in patients with hematologic and solid tumor malignancies receiving anti-cancer therapy [1].Its use has also been associated with increased financial burden and morbidity when used inappropriately.When used in patients who are deficient in glucose-6-phosphate dehydrogenase (G6PD), it often results in life threatening acute hemolytic anemia.We report an interesting case of a 74-year-old female treated with rasburicase for presumed tumor lysis syndrome (TLS) who later developed acute hemolytic anemia secondary to G6PD deficiency.Here we highlight and emphasize how to minimize inappropriate use of rasburicase and how to recognize patients with increased risk for developing G6PD deficiency.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19767382","pmcid":null,"openalex_id":"https://openalex.org/W4399675180","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.17545892,"influential_citations":0,"citation_trend":[],"oa_status":"gold","license":"cc-by-nc","oa_locations":[{"url":"https://irispublishers.com/accs/pdf/ACCS.MS.ID.000571.pdf","host_type":"journal"},{"url":"https://irispublishers.com/accs/pdf/ACCS.MS.ID.000571.pdf","host_type":"publisher"},{"url":"http://dx.doi.org/10.33552/accs.2024.03.000571","host_type":"journal"}],"fields_of_study":["Methemoglobinemia and Tumor Lysis Syndrome","Neonatal Health and Biochemistry","Blood disorders and treatments"],"mesh_terms":[],"keywords":["Glucose-6-phosphate dehydrogenase deficiency","Rasburicase","Hemolysis","Glucosephosphate Dehydrogenase Deficiency","Glucose-6-phosphate dehydrogenase","Medicine","Dehydrogenase","Internal medicine","Endocrinology","Biochemistry","Biology","Uric acid","Enzyme","Hyperuricemia"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Zero hunger"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-09T12:46:55.030016Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}