{"doi":"10.3349/ymj.2022.63.5.413","title":"Platelet Function and Genotype after DES Implantation in East Asian Patients: Rationale and Characteristics of the PTRG-DES Consortium","abstract":null,"journal":"Yonsei Medical Journal","year":2022,"id":622301,"datarank":0.5709993734655481,"base_score":3.8066624897703196,"endowment":3.8066624897703196,"self_citation_contribution":0.5709993734655481,"citation_network_contribution":0.0,"self_endowment_contribution":0.5709993734655481,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":44,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":4,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1607798,"name":"Young-Hoon Jeong","orcid":"0000-0003-0403-3726","position":1,"is_corresponding":false},{"id":1607799,"name":"Byeong-Keuk Kim","orcid":"0000-0003-2493-066X","position":2,"is_corresponding":false},{"id":1607802,"name":"Hyung Joon Joo","orcid":"0000-0003-1846-8464","position":3,"is_corresponding":false},{"id":31944,"name":"Kiyuk Chang","orcid":"0000-0003-3456-8705","position":4,"is_corresponding":false},{"id":1607805,"name":"Yongwhi Park","orcid":"0000-0003-3626-9717","position":5,"is_corresponding":false},{"id":1607808,"name":"Young Bin Song","orcid":"0000-0003-3986-9152","position":6,"is_corresponding":false},{"id":1607809,"name":"Sung Gyun Ahn","orcid":"0000-0002-1528-2739","position":7,"is_corresponding":false},{"id":1607811,"name":"Jung-Won Suh","orcid":"0000-0002-0397-6071","position":8,"is_corresponding":false},{"id":31947,"name":"Sang Yeub Lee","orcid":"0000-0003-1386-349X","position":9,"is_corresponding":false},{"id":1352146,"name":"Jung Rae Cho","orcid":"0000-0002-9803-6612","position":10,"is_corresponding":false},{"id":786969,"name":"Hyo‐Soo Kim","orcid":"0000-0003-0847-5329","position":11,"is_corresponding":false},{"id":1607813,"name":"Moo Hyun Kim","orcid":"0000-0003-3468-6453","position":12,"is_corresponding":false},{"id":1607815,"name":"Do-Sun Lim","orcid":"0000-0001-5751-5177","position":13,"is_corresponding":false},{"id":31932,"name":"Eun-Seok Shin","orcid":"0000-0002-9169-6968","position":14,"is_corresponding":false},{"id":31950,"name":"Ae-Young Her","orcid":"0000-0002-9990-6843","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Platelet Function and Genotype after DES Implantation in East Asian Patients: Rationale and Characteristics of the PTRG-DES Consortium","abstract":"PURPOSE: Platelet function test (PFT) results and genotype hold unique prognostic implications in East Asian patients. The aim of the PTRG-DES (Platelet function and genoType-Related long-term proGnosis in Drug-Eluting Stent-treated Patients with coronary artery disease) consortium is to assess the clinical impact thereof on long-term clinical outcomes in Korean patients with coronary artery disease during dual antiplatelet therapy (DAPT) including clopidogrel. MATERIALS AND METHODS: Searching publications on the PubMed, we reviewed clopidogrel treatment studies with PFT and/or genotype data for potential inclusion in this study. Lead investigators were invited to share PFT/genotype results, patient characteristics, and clinical outcomes to evaluate relationships among them. RESULTS: 3) were 47.9% (intermediate metabolizers) and 14.2% (poor metabolizers), respectively. CONCLUSION: The PTRG-DES consortium highlights unique values for on-clopidogrel platelet reactivity and CYP2C19 phenotype that may be important to developing optimal antiplatelet regimens in East Asian patients. 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