{"doi":"10.3233/jpd-212935","title":"Recruitment for Remote Decentralized Studies in Parkinson’s Disease","abstract":"BACKGROUND: Traditional in-person Parkinson's disease (PD) research studies are often slow to recruit and place unnecessary burden on participants. The ongoing COVID-19 pandemic has added new impetus to the development of new research models. OBJECTIVE: To compare recruitment processes and outcomes of three remote decentralized observational PD studies with video visits. METHODS: We examined the number of participants recruited, speed of recruitment, geographic distribution of participants, and strategies used to enhance recruitment in FIVE, a cross-sectional study of Fox Insight participants with and without PD (n = 203); VALOR-PD, a longitudinal study of 23andMe, Inc. research participants carrying the LRRK2 G2019S variant with and without PD (n = 277); and AT-HOME PD, a longitudinal study of former phase III clinical trial participants with PD (n = 226). RESULTS: Across the three studies, 706 participants from 45 U.S. states and Canada enrolled at a mean per study rate of 4.9 participants per week over an average of 51 weeks. The cohorts were demographically homogenous with regard to race (over 95%white) and level of education (over 90%with more than a high school education). The number of participants living in primary care Health Professional Shortage Areas in each study ranged from 30.3-42.9%. Participants reported interest in future observational (98.5-99.6%) and interventional (76.1-87.6%) research studies with remote video visits. CONCLUSION: Recruitment of large, geographically dispersed remote cohorts from a single location is feasible. Interest in participation in future remote decentralized PD studies is high. More work is needed to identify best practices for recruitment, particularly of diverse participants.","journal":"Journal of Parkinson s Disease","year":2021,"id":175839,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":22,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9499,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":317503,"name":"Erika F. Augustine","orcid":"0000-0001-7257-8985","position":1,"is_corresponding":false},{"id":483717,"name":"Elizabeth Baloga","orcid":null,"position":2,"is_corresponding":false},{"id":483714,"name":"Margaret Daeschler","orcid":null,"position":3,"is_corresponding":false},{"id":5038,"name":"Paul Cannon","orcid":null,"position":4,"is_corresponding":false},{"id":717650,"name":"Helen Rowbotham","orcid":null,"position":5,"is_corresponding":false},{"id":717651,"name":"Eli Chanoff","orcid":null,"position":6,"is_corresponding":false},{"id":317506,"name":"Stella Jensen-Roberts","orcid":"0000-0001-7269-3502","position":7,"is_corresponding":false},{"id":663146,"name":"Julia Soto","orcid":"0000-0001-7885-862X","position":8,"is_corresponding":false},{"id":92201,"name":"Robert G. Holloway","orcid":"0000-0002-1448-163X","position":9,"is_corresponding":false},{"id":341997,"name":"Connie Marras","orcid":"0000-0002-9236-9328","position":10,"is_corresponding":false},{"id":246443,"name":"Caroline M. Tanner","orcid":"0000-0002-3775-5082","position":11,"is_corresponding":false},{"id":22466,"name":"E. Ray Dorsey","orcid":null,"position":12,"is_corresponding":false},{"id":317514,"name":"Ruth B. Schneider","orcid":"0000-0001-8094-4041","position":13,"is_corresponding":false},{"id":717649,"name":"Taylor L. Myers","orcid":null,"position":0,"is_corresponding":true}],"reference_count":23,"raw_metadata":null,"created_at":"2026-07-18T23:47:15.431199Z","pmid":"34744053","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}