{"doi":"10.3174/ajnr.a7032","title":"Severity of Chest Imaging is Correlated with Risk of Acute Neuroimaging Findings among Patients with COVID-19","abstract":"BACKGROUND AND PURPOSE: Severe respiratory distress in patients with COVID-19 has been associated with higher rate of neurologic manifestations. Our aim was to investigate whether the severity of chest imaging findings among patients with coronavirus disease 2019 (COVID-19) correlates with the risk of acute neuroimaging findings. MATERIALS AND METHODS: This retrospective study included all patients with COVID-19 who received care at our hospital between March 3, 2020, and May 6, 2020, and underwent chest imaging within 10 days of neuroimaging. Chest radiographs were assessed using a previously validated automated neural network algorithm for COVID-19 (Pulmonary X-ray Severity score). Chest CTs were graded using a Chest CT Severity scoring system based on involvement of each lobe. Associations between chest imaging severity scores and acute neuroimaging findings were assessed using multivariable logistic regression. RESULTS: = .041). The pulmonary x-ray severity score was a significant predictor of acute neuroimaging findings in patients with COVID-19. CONCLUSIONS: Patients with COVID-19 and acute neuroimaging findings had more severe findings on chest imaging on both radiographs and CT compared with patients with COVID-19 without acute neuroimaging findings. The severity of findings on chest radiography was a strong predictor of acute neuroimaging findings in patients with COVID-19.","journal":"American Journal of Neuroradiology","year":2021,"id":190613,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":13,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7235,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":256377,"name":"Matthew Li","orcid":"0000-0002-6207-4940","position":1,"is_corresponding":false},{"id":754875,"name":"Ke Jiang","orcid":"0000-0001-7644-6752","position":2,"is_corresponding":false},{"id":754876,"name":"Byung Chul Yoon","orcid":"0000-0003-2929-5677","position":3,"is_corresponding":false},{"id":256382,"name":"Dexter P. Mendoza","orcid":"0000-0001-7571-740X","position":4,"is_corresponding":false},{"id":736031,"name":"Efrén J. Flores","orcid":"0000-0003-1398-0426","position":5,"is_corresponding":false},{"id":465317,"name":"Sandra Rincon","orcid":"0000-0001-7210-0711","position":6,"is_corresponding":false},{"id":465318,"name":"William A. Mehan","orcid":"0000-0003-4655-7165","position":7,"is_corresponding":false},{"id":364087,"name":"John Conklin","orcid":"0000-0001-9921-2086","position":8,"is_corresponding":false},{"id":263270,"name":"Susie Y. Huang","orcid":"0000-0003-2950-7254","position":9,"is_corresponding":false},{"id":754877,"name":"Angela L. Lang","orcid":"0000-0002-2355-0414","position":10,"is_corresponding":false},{"id":754878,"name":"Duc M. Giao","orcid":"0000-0002-4053-7692","position":11,"is_corresponding":false},{"id":465319,"name":"Thabele M Leslie‐Mazwi","orcid":"0000-0002-4191-2466","position":12,"is_corresponding":false},{"id":14567,"name":"Jayashree Kalpathy–Cramer","orcid":"0000-0001-8906-9618","position":13,"is_corresponding":false},{"id":106867,"name":"Brent P. Little","orcid":"0000-0001-6657-8241","position":14,"is_corresponding":false},{"id":465316,"name":"Karen Buch","orcid":"0000-0001-9579-8921","position":15,"is_corresponding":false},{"id":256383,"name":"Min Lang","orcid":"0000-0002-3895-5342","position":0,"is_corresponding":true}],"reference_count":41,"raw_metadata":null,"created_at":"2026-07-18T23:49:26.966524Z","pmid":"33541897","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}