{"doi":"10.3174/ajnr.a6877","title":"Brain MR Spectroscopic Findings in 3 Consecutive Patients with COVID-19: Preliminary Observations","abstract":"Brain multivoxel MR spectroscopic imaging was performed in 3 consecutive patients with coronavirus disease 2019 (COVID-19). These included 1 patient with COVID-19-associated necrotizing leukoencephalopathy, another patient who had a recent pulseless electrical activity cardiac arrest with subtle white matter changes, and a patient without frank encephalopathy or a recent severe hypoxic episode. The MR spectroscopic imaging findings were compared with those of 2 patients with white matter pathology not related to Severe Acute Respiratory Syndrome coronavirus 2 infection and a healthy control subject. The NAA reduction, choline elevation, and glutamate/glutamine elevation found in the patient with COVID-19-associated necrotizing leukoencephalopathy and, to a lesser degree, the patient with COVID-19 postcardiac arrest, follow a similar pattern as seen with the patient with delayed posthypoxic leukoencephalopathy. Lactate elevation was most pronounced in the patient with COVID-19 necrotizing leukoencephalopathy.","journal":"American Journal of Neuroradiology","year":2020,"id":69409,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":21,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8635,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":367510,"name":"Akila Weerasekera","orcid":"0000-0003-0446-7604","position":1,"is_corresponding":false},{"id":367511,"name":"Sarah J. Moum","orcid":"0000-0002-8282-2619","position":2,"is_corresponding":false},{"id":368246,"name":"Katharina Eikermann‐Haerter","orcid":null,"position":3,"is_corresponding":false},{"id":109379,"name":"Brian L. Edlow","orcid":"0000-0001-7235-8456","position":4,"is_corresponding":false},{"id":196790,"name":"David Fischer","orcid":"0000-0001-8181-0643","position":5,"is_corresponding":false},{"id":331632,"name":"Ángel Torrado-Carvajal","orcid":"0000-0002-1540-2809","position":6,"is_corresponding":false},{"id":267287,"name":"Marco L. Loggia","orcid":"0000-0002-8026-5265","position":7,"is_corresponding":false},{"id":311025,"name":"Shibani S. Mukerji","orcid":"0000-0002-5677-6954","position":8,"is_corresponding":false},{"id":307822,"name":"Pamela W. Schaefer","orcid":"0000-0002-4222-6134","position":9,"is_corresponding":false},{"id":367512,"name":"R. Gilberto González","orcid":"0000-0002-0234-3897","position":10,"is_corresponding":false},{"id":241417,"name":"Michael H. Lev","orcid":"0000-0003-0236-7319","position":11,"is_corresponding":false},{"id":335177,"name":"Eva‐Maria Ratai","orcid":"0000-0001-9476-6207","position":12,"is_corresponding":false},{"id":226557,"name":"Otto Rapalino","orcid":"0000-0002-5038-4183","position":0,"is_corresponding":true}],"reference_count":25,"raw_metadata":null,"created_at":"2026-07-18T21:42:22.705573Z","pmid":"33122208","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}