{"doi":"10.31579/2640-1045/128","title":"Commentary on Article: The Role of PPM1D in Cancer and Advances in Studies of its Inhibitors","abstract":"The review article entitled \"The role of PPM1D in cancer and advances in studies of its inhibitors\" provides a comprehensive overview of the current understanding of the function of PPM1D in cancer and the progress that has been made in the development of inhibitors to target this protein. PPM1D, also known as WIP1, is a serine/threonine phosphatase that plays a key role in regulating several cellular processes including DNA damage response, cell cycle progression, and apoptosis. Dysregulation of PPM1D has been implicated in various types of cancer, and this article delves into the molecular mechanisms by which PPM1D overexpression can promote tumorigenesis.","journal":"Endocrinology and Disorders","year":2023,"id":415574,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.924,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":597357,"name":"Yong Wu","orcid":"0000-0003-1126-3271","position":0,"is_corresponding":true}],"reference_count":11,"raw_metadata":null,"created_at":"2026-07-19T01:22:12.933438Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}