{"doi":"10.31438/trf.hh2024.61","title":"3D PRINTED MICRO LIQUID THERMAL REGULATOR (MLTR) FOR IN-VIVO CHRONIC PAIN APPLICATIONS","abstract":"The micro-liquid thermal regulator, or MLTR, is a novel 3Dprinted implantable device for in-vivo thermoregulation tests.The efficient micro-manifold design within the device allows for minimal water pressure yet high liquid throughput, creating an efficient thermoregulation effect.Upon activation, the device demonstrates impressive capabilities, swiftly lowering surface temperatures from ambient room temperature of 25.3C to 14.4C.This capacity to achieve temperatures below 37C, which is the physical norm, holds promise for influencing physiological processes associated with pain transmission.Future applications anticipate the implantation of the MLTR onto the dorsal root ganglia for comprehensive testing, furthering its potential in advancing research and therapeutics.","journal":null,"year":2024,"id":508553,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9561,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1360575,"name":"Ronald F. Childs","orcid":null,"position":1,"is_corresponding":false},{"id":918187,"name":"Lei Zhai","orcid":"0000-0002-3886-2154","position":2,"is_corresponding":false},{"id":572955,"name":"Zixi Cheng","orcid":"0000-0002-7941-8527","position":3,"is_corresponding":false},{"id":270509,"name":"Swaminathan Rajaraman","orcid":"0000-0003-2279-2013","position":4,"is_corresponding":false},{"id":926344,"name":"Jazune Madas","orcid":null,"position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-19T02:11:10.049781Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}