{"doi":"10.31438/trf.hh2022.21","title":"PASSIVE 3D-PRINTED FULLY ELASTIC PILL FOR SAMPLING OF GUT MICROBIOME","abstract":"Sampling of gut microbiome upstream of the colon is challenging and expensive. Research has shown that ingestible devices are effective in sampling microbiome, however existing designs are complex and suffer from high levels of contamination from untargeted regions. This paper aims to present a simple sampling design concept with a self-closing mechanism relying on swellable polyacrylate beads that close the inlet to prevent contamination. The pill is fully elastic, lightweight, biocompatible, battery-less realized using stereo-lithography based 3D-printer. Herein, it is believed that such an ingestible device will increase the understanding of spatial diversity of gut microbiome and its response to medical conditions and treatments, using a noninvasive and simple technique.","journal":null,"year":2022,"id":314457,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9489,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1013204,"name":"Cihan Asci","orcid":"0009-0009-3972-6099","position":1,"is_corresponding":false},{"id":1013205,"name":"Rachel E. Owyeung","orcid":"0000-0001-6225-2906","position":2,"is_corresponding":false},{"id":1013206,"name":"Giovanni Widmer","orcid":"0000-0001-7255-3761","position":3,"is_corresponding":false},{"id":1013207,"name":"Sameer Sonkusale","orcid":"0000-0003-3579-910X","position":4,"is_corresponding":false},{"id":1013203,"name":"Ruben Del‐Rio‐Ruiz","orcid":"0000-0002-1031-6602","position":0,"is_corresponding":true}],"reference_count":9,"raw_metadata":null,"created_at":"2026-07-19T00:33:52.047924Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}