{"doi":"10.31254/phyto.2017.6105","title":"Analgesic and anti-Inflammatory activity of Tradescantia fluminensis leaves extract","abstract":"<jats:p>Objective: The present study sought to evaluate the anti-inflammatory and analgesic activities of ethanolic extract from Tradescantia fluminensis leaves. Methods: The crude leaf extract of T. fluminensis was investigated for anti-inflammatory and analgesic activities in Wistar Albino rats and mice respectively. The anti-inflammatory activity was investigated using egg albumin induced oedema model while acetic acid and formalin-induced paw licking models were used to evaluate the analgesic activity. Results: The extract showed a significant (P&lt;0.05) dose-dependent inhibition of inflammation and pain compared to the control group. Conclusion: The leaf extract possesses anti-inflammatory and analgesic activities. The activities could be attributed to phytochemicals present in the plant.</jats:p>","journal":"The Journal of Phytopharmacology","year":2017,"id":42683,"datarank":0.31161552036926643,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.07019983350415133,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.07019983350415133,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":3,"citers_with_citation_signal":2,"citers_with_endowment":2,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":203973,"name":"Lawrence Obado Osuwat","orcid":null,"position":1,"is_corresponding":false},{"id":203974,"name":"Connie Wambui Mureithi","orcid":null,"position":2,"is_corresponding":false},{"id":203972,"name":"Wilson Rwai Wawer","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"18998881","pmcid":null,"openalex_id":"https://openalex.org/W3204374287","authors":[],"funders":[],"total_grants":0,"fwci":0.4785,"citation_percentile":0.70423196,"influential_citations":0,"citation_trend":[{"year":2017,"count":1},{"year":2019,"count":1},{"year":2022,"count":1},{"year":2023,"count":1}],"oa_status":"bronze","license":null,"oa_locations":[{"url":"https://doi.org/10.31254/phyto.2017.6105","host_type":"journal"},{"url":"https://doi.org/10.31254/phyto.2017.6105","host_type":"BRONZE"},{"url":"https://doi.org/10.31254/phyto.2017.6105","host_type":"publisher"},{"url":"http://doi.org/10.31254/phyto.2017.6105","host_type":"journal"}],"fields_of_study":["Computational Drug Discovery Methods","Drug-Induced Hepatotoxicity and Protection","Essential Oils and Antimicrobial Activity","Medicine"],"mesh_terms":[],"keywords":["Licking","Analgesic","Anti-inflammatory","Traditional medicine","Chemistry","Pharmacology","Medicine"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-14T04:45:17.408821Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}