{"doi":"10.31254/jsir.2015.4203","title":"A simple slide test for erythrocyte aggregability as a risk stratification tool in patients admitted with chest pain to the emergency room","abstract":"<jats:p>Patients presenting to the Emergency Room with chest pain pose a diagnostic challenge because of a possible acute coronary syndrome. This study was done to determine the diagnostic utility of a simple slide test for red cell aggregability in patients with chest pain and as a prognostic indicator in unstable angina. 32 patients of Unstable Angina and 32 persons with non-cardiac chest pain were included in the study. A simple slide was prepared with the peripheral blood of the subjects and stained and assessed by a pathologist and by digital photographs and grid analysis to grade red cell aggregabilty. 19 patients with Unstable Angina had Grade C or D red cell aggregation while only 2 persons with noncardiac chest pain had Grade C aggregation. Estimation of Erythrocyte Percentage from the grid images and calculation of Receiver Operating Characteristic Curve gave a best cutoff value of 60-70 with a lower EP signifying unstable angina. 8 patients with Unstable Angina and an EP &lt;50 developed acute MI or recurrent angina. To conclude, a simple slide test of the peripheral blood helps in the initial evaluation of chest pain patients for possible unstable angina, and, further has prognostic utility in patients with unstable angina.</jats:p>","journal":"Journal of Scientific and Innovative Research","year":2015,"id":613403,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1580270,"name":"Ravi Venkatachelam Chitrapu","orcid":null,"position":1,"is_corresponding":false},{"id":1580271,"name":"Ram Manohar Talupula","orcid":null,"position":2,"is_corresponding":false},{"id":1580272,"name":"Uma Prasad","orcid":null,"position":4,"is_corresponding":false},{"id":1580274,"name":"Bhagyalakshmi Atla","orcid":null,"position":6,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"A simple slide test for erythrocyte aggregability as a risk stratification tool in patients admitted with chest pain to the emergency room","abstract":"<jats:p>Patients presenting to the Emergency Room with chest pain pose a diagnostic challenge because of a possible acute coronary syndrome. This study was done to determine the diagnostic utility of a simple slide test for red cell aggregability in patients with chest pain and as a prognostic indicator in unstable angina. 32 patients of Unstable Angina and 32 persons with non-cardiac chest pain were included in the study. A simple slide was prepared with the peripheral blood of the subjects and stained and assessed by a pathologist and by digital photographs and grid analysis to grade red cell aggregabilty. 19 patients with Unstable Angina had Grade C or D red cell aggregation while only 2 persons with noncardiac chest pain had Grade C aggregation. Estimation of Erythrocyte Percentage from the grid images and calculation of Receiver Operating Characteristic Curve gave a best cutoff value of 60-70 with a lower EP signifying unstable angina. 8 patients with Unstable Angina and an EP &lt;50 developed acute MI or recurrent angina. To conclude, a simple slide test of the peripheral blood helps in the initial evaluation of chest pain patients for possible unstable angina, and, further has prognostic utility in patients with unstable angina.</jats:p>","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"23304386","pmcid":null,"openalex_id":"https://openalex.org/W4301669253","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.41756251,"influential_citations":0,"citation_trend":[],"oa_status":"bronze","license":null,"oa_locations":[{"url":"https://doi.org/10.31254/jsir.2015.4203","host_type":"journal"},{"url":"https://doi.org/10.31254/jsir.2015.4203","host_type":"publisher"},{"url":"http://doi.org/10.31254/jsir.2015.4203","host_type":"journal"}],"fields_of_study":["Acute Myocardial Infarction Research","Sepsis Diagnosis and Treatment","Blood properties and coagulation"],"mesh_terms":[],"keywords":["Medicine","Chest pain","Unstable angina","Angina","Cardiology","Internal medicine","Acute coronary syndrome","Receiver operating characteristic","Myocardial infarction"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-02T07:58:22.483440Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}