{"doi":"10.31234/osf.io/uj5xd","title":"Examining time-varying dynamics of co-occurring depressed mood and social anxiety","abstract":"Dimensional frameworks of psychopathology (e.g., HiTOP models) call for multivariate approaches to map co-occurring symptoms clustered within spectra to index what symptoms emerge when and for whom. However, previous work measuring symptom dynamics and affective experiences has largely neglected transdiagnostic measurement of how symptoms co-vary between- and within-individuals over time. Ecological momentary assessment (EMA) offers a method for assessing and differentiating the dynamics of co-occurring symptoms with greater temporal granularity and naturalistic context. The present study used multivariate mixed effects location-scale modeling to characterize the time-varying dynamics of depressed mood and anxiety for women diagnosed with social anxiety disorder, major depression, and related co-occurring diagnoses. Women completed five daily EMA surveys over 30 days (150 EMA surveys/woman, T 5,250 total observations) and two clinical diagnostic and self-report batteries conducted approximately two months apart. There was evidence of lagged effects within-factor (bs = .08-.09), but not cross-factor (bs &amp;lt; .01) during EMA. Symptoms co-varied such that momentary spikes from one’s typical level of anxiety were associated with increases in momentary depressed mood (b = .19) and greater volatility of depressed mood (b = .06). Similarly, spikes from one’s typical levels of depressed mood were associated with increases in momentary anxiety (b = .19). Furthermore, the presence and magnitude of effects demonstrated person-specific heterogeneity. Findings from this work help to characterize how daily experiences of co-occurring mood and anxiety fluctuate and offer insight to aid the development of momentary, person-specific interventions designed to regulate symptom fluctuations.","journal":"PsyArXiv (OSF Preprints)","year":2021,"id":225572,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9401,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":673796,"name":"Madelyn Frumkin","orcid":"0000-0002-3122-4483","position":1,"is_corresponding":false},{"id":828332,"name":"KATIE SPINK","orcid":null,"position":2,"is_corresponding":false},{"id":456777,"name":"Natasha Tonge","orcid":"0000-0001-7670-7991","position":3,"is_corresponding":false},{"id":827993,"name":"Katherine T. Foster","orcid":"0000-0002-3561-6687","position":4,"is_corresponding":false},{"id":456779,"name":"Marilyn L. Piccirillo","orcid":"0000-0002-4616-5180","position":0,"is_corresponding":true}],"reference_count":27,"raw_metadata":null,"created_at":"2026-07-18T23:54:26.581453Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}